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Understanding the tau tangles in neurodegeneration could aid treatment discovery

21 January 2022 | By Mandy Parrett (Drug Target Review)

Representing a breakthrough in better understanding how tau proteins cause neurodegenerative disease, scientists have mapped the tau interactome.

news

Gene linked to rare disorder also regulates key enzyme in Alzheimer’s

22 August 2019 | By Rachael Harper (Drug Target Review)

A gene associated with a rare balance disorder also regulates the behaviour of an enzyme that increases the risk for Alzheimer's disease.

news

Researchers image structure of cancer metastasis target

22 August 2019 | By Victoria Rees (Drug Target Review)

The structure of a key receptor involved in tumour metastasis has been imaged in a study, providing opportunities to develop cancer treatments.

news

Four cell types discovered in glioblastoma tumours

12 August 2019 | By Victoria Rees (Drug Target Review)

A new study has revealed that glioblastomas contain four different types of cell which the researchers say should be treated separately.

news

Interferon pathway could provide drug target for cancers

8 August 2019 | By Victoria Rees (Drug Target Review)

A study has found that signals from interferons can be blocked, allowing the immune system to attack tumours which provides a potential target.

news

New target identified for vestibular diseases

10 July 2019 | By Victoria Rees (Drug Target Review)

Researchers have discovered a potential treatment for vestibular conditions such as dizziness in animal models.

news

Researchers develop directed evolution technique

8 July 2019 | By Victoria Rees (Drug Target Review)

New method for directed evolution could improve gene therapies and generic drug development.

news

Study reveals antioxidant role in spread of lung cancer

1 July 2019 | By Victoria Rees (Drug Target Review)

Researchers have discovered that lung cancer cells metastasise using antioxidants, informing potential future therapies.

news

Researchers identify chemotherapy-enhancing molecule

10 June 2019 | By Victoria Rees (Drug Target Review)

A new study has found a small molecule which prevents cancer cells from mutating and becoming resistant to chemotherapy.

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