Children's National Hospital

news

Promising new gene therapy approach for LGMD2B

5 January 2022 | By Mandy Parrett (Drug Target Review)

Researchers at Children’s National Hospital in the US have developed a promising new gene therapy for limb-girdle muscular dystrophy (LGMD) 2B.

news

Signalling pathway identified as target against paediatric glioma

25 August 2021 | By Anna Begley (Drug Target Review)

Researchers have found a vulnerability in a developmental signalling pathway, presenting a target for paediatric low-grade glioma formation.

news

New mouse model could be used to develop better HIV treatments

17 May 2021 | By Victoria Rees (Drug Target Review)

A new pre-clinical mouse model could enable the study of HIV infection and the testing of cell therapies against the virus.

news

Tumour cell vaccine strategy developed for neuroblastoma and melanoma

1 April 2021 | By Victoria Rees (Drug Target Review)

A combination of checkpoint and small molecule inhibitors showed success at targeting Myc oncogenes in mouse neuroblastoma and melanoma models.

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Experimental mouse model of Duchenne muscular dystrophy developed

2 April 2020 | By Victoria Rees (Drug Target Review)

Researchers have created an accurate mouse model of Duchenne muscular dystrophy (DMD), showing that TGFβ is a potential target for the condition.