news Promising new gene therapy approach for LGMD2B 5 January 2022 | By Mandy Parrett (Drug Target Review) Researchers at Children’s National Hospital in the US have developed a promising new gene therapy for limb-girdle muscular dystrophy (LGMD) 2B.
news Signalling pathway identified as target against paediatric glioma 25 August 2021 | By Anna Begley (Drug Target Review) Researchers have found a vulnerability in a developmental signalling pathway, presenting a target for paediatric low-grade glioma formation.
news New mouse model could be used to develop better HIV treatments 17 May 2021 | By Victoria Rees (Drug Target Review) A new pre-clinical mouse model could enable the study of HIV infection and the testing of cell therapies against the virus.
news Tumour cell vaccine strategy developed for neuroblastoma and melanoma 1 April 2021 | By Victoria Rees (Drug Target Review) A combination of checkpoint and small molecule inhibitors showed success at targeting Myc oncogenes in mouse neuroblastoma and melanoma models.
news Experimental mouse model of Duchenne muscular dystrophy developed 2 April 2020 | By Victoria Rees (Drug Target Review) Researchers have created an accurate mouse model of Duchenne muscular dystrophy (DMD), showing that TGFβ is a potential target for the condition.