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Microbiota composition influences respiratory virus susceptibility
The interactions linking intestinal microbiota with the functionality of basally resident alveolar macrophages and severity of infection are revealed.
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Georgia State University
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ProAgio drug shows success against solid tumours in mice
Studies in mice have shown that the drug ProAgio is effective at treating pancreatic cancer and triple-negative breast cancer.
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Severe symptoms of COVID-19 are caused by brain infection in mice, finds study
Researchers found that SARS-CoV-2 persists in the brain after it is cleared in the lungs and concluded the severest and longest lasting symptoms of COVID-19 may be caused by brain infection.
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Oral drug blocks SARS-CoV-2 transmission in ferrets, researchers find
A team has found that their drug Molnupiravir (MK-4482/EIDD-2801) acts as an antiviral against SARS-CoV-2 in pre-clinical studies.
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Two cytokines found to cure and prevent rotavirus infection in mice
Researchers have found that the cytokines IL-18 and IL-22 can combat and cure rotavirus infections in mice.
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Mutant form of Ebola could be used in vaccine development
A study has shown that a mutated form of the Ebola virus protects macaque models against the disease, demonstrating an opportunity for a drug target.
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Drug targets for Dengue, Zika and Ebola viruses
US researchers have identified possible drug targets for Dengue, Zika and Ebola viruses…
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Arc protein ‘switch off’ essential for cognitive flexibility
An international team of scientists has discovered that memory, learning and cognitive flexibility depend on a 'switch off' of the Arc protein in the brain, which could enable us to better understand and combat neurological diseases that inhibit memory, such as Alzheimer's.
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FUNDC1 protein in cardiac muscle cells linked to heart failure
Reducing a protein found in the mitochondria of cardiac muscle cells initiates cardiac dysfunction and heart failure...
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Nanoparticles show promise for treating inflammatory bowel disease
8 April 2016 | By Victoria White
Nanoparticles designed to block a cell-surface molecule that plays a key role in inflammation could be a safe treatment for inflammatory bowel disease...
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Scientists discover dual role of IL-36 in inflammatory bowel disease
17 February 2016 | By Victoria White
Scientists have discovered the dual role of IL-36 in both promoting intestinal inflammation and resolving or healing that inflammation in IBD...
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New biomarkers may influence cancer drug design
22 January 2016 | By Victoria White
The research from Georgia State University scientists provides strong translational potential with respect to biomarkers that play critical roles in the development of endometrial/lung tumours...