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Scientists discover a small molecule that halts kidney disease progression
A team of researchers set out to discover the disease pathways of a rare genetic kidney disease and found a compound that stops the disease in its tracks.
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Harvard Medical School
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Tumour cell biology reveals characteristic that causes metastasis
A collaborative team of researchers in the US have uncovered characteristics of tumour cells that are linked to cancer metastasis.
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Lung tumours communicate with bones to progress disease
Scientists at Massachusetts General Hospital (MGH) have identified how a type of lung cancer co-opts a portion of the immune system via bone marrow to increase tumour progression.
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Molecular pathway offers treatment targets for pulmonary fibrosis
A study has identified a molecular pathway that appears to be critical to the development of fibrosis...
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Power of radiomics to improve precision medicine
Data mining of medical images with radiomics offers clinicians a way to characterise lung tumours and improve precision medicine...
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Bioprinted veins reveal new drug diffusion details
A scientific collaboration has developed vascularised 3-D bioprinted liver tissue constructs, providing more precise drug toxicity testing...
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New botulinum neurotoxin discovered
Researchers have identified a new toxin, botulinum neurotoxin type X (BoNT/X), that has the potential to open up a new field of toxin therapeutics...
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Lymph node metastases may not always be source of cancer’s spread
A study led has found that the model for the spread of carcinoma - from the primary tumour, to nearby lymph nodes, to other organs - may not apply in all cases.
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New study links neuropilin 2 deficiency to inflammation-induced edema & lymphedema
14 October 2016 | By Niamh Louise Marriott, Digital Content Producer
The Nrp2 knockout mice showed massively increased and prolonged edema following inflammation. Investigation into this finding led Bielenberg's laboratory...
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Interview with Michael Springer, Associate Professor of Systems Biology, Harvard Medical School
17 March 2016 | By Caroline Richards
Caroline Richards, Editor of Drug Target Review, invites Michael Springer, Associate Professor of Systems Biology, Harvard Medical School to discuss a laboratory study of a yeast model using microfluidic systems...
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Researchers resurrect ancient virus to improve gene therapy
31 July 2015 | By Victoria White
Researchers have reconstructed an ancient virus that is highly effective at delivering gene therapies to the liver, muscle, and retina...
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Anti-malaria drugs could be a potential treatment for Parkinson’s disease
17 July 2015 | By Victoria White
Scientists have found that existing anti-malaria drugs, Chloroquine and Amodiaquine, could be a potential treatment for Parkinson's disease...