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AI system produces binding proteins using limited target information
New software can make protein molecules that bind with high affinity and specificity to many biomarkers, including human hormones.
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Howard Hughes Medical Institute
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Latest developments in COVID-19 research
As COVID-19 continues to evolve, researchers are still on the lookout for new ways to protect against the virus. Drug Target Review brings you some of the most recent pre-clinical developments.
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COVID-19 booster jabs provide protection against Omicron variants
Researchers have found that current vaccine boosters offer sufficient immune protection against severe symptoms from Omicron.
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Study reveals how SARS-CoV-2 rewires human proteins for replication
A team of researchers has analysed how SARS-CoV-2 hijacks the proteins in its host cells to aid replication and infect nearby cells.
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GREB1 gene potential drug target for prostate cancer treatment
Researchers in the US have discovered how a gene involved in regulating hormone receptors, GREB1, may contribute to drug resistance in some prostate cancer patients.
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CRISPR used to prevent cancers tied to EBV and KSHV
Researchers have discovered a possible path forward in preventing the development of cancers tied to two viruses, including the virus that causes infectious mononucleosis...
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DNA gets away: Scientists catch the rogue molecule that can trigger autoimmunity
A research team has discovered the process - and filmed the actual moment - that can change the body’s response to a dying cell.
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CRISPR prevents hearing loss in mice
Researchers use CRISPR-Cas9 to target a mutation in the Tmc1 gene that causes the loss of hair cells in the inner ear.
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Metabolic collaboration linked to Alzheimer’s disease
Researchers have discovered that impairing a critical partnership between brain cells can lead to neurodegeneration...
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Gene therapy may lower risk for heart disease
Researchers have tested whether a single injection of the gene, LeXis could slow down the development of heart disease...
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Breakthrough method yields trove of neuronal subtypes and gene regulators
Researchers have discovered a trove of neuronal subtypes and gene regulators, using a new method they developed called snmC-seq...
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Researchers find key molecule that could lead to new anaemia therapies
Researchers find key molecule that could lead to new therapies for anaemia and other iron disorders.