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D-PDMP reverses hair loss and skin damage linked to fatty diet
In a series of experiments, researchers have used an experimental compound to successfully reverse hair loss, hair whitening and skin inflammation...
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Experimental drug stops Parkinson’s disease progression in mice
Researchers say they have developed an experimental drug, similar to compounds used to treat diabetes, that slows the progression of Parkinson's disease...
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Mitochondrial DNA could predict risk for sudden cardiac death
New studies add to evidence of link between mitochondrial DNA copy number and risk for cardiovascular disease...
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‘Immunoswitch’ particles may be key to more effective cancer immunotherapy
Scientists have created a nanoparticle that carries two different antibodies capable of simultaneously switching off cancer cells’ defensive properties while switching on a robust anti-cancer immune response in mice.
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New mouse model suggests how Alzheimer’s causes dementia
4 July 2016 | By Victoria White, Digital Content Producer
Using a mouse model that mimics the development of Alzheimer’s, scientists have determined the biological “insults” that must occur to cause dementia...
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Proteogenomics provides new inroads to ovarian cancer treatments
29 June 2016 | By Victoria White, Digital Content Producer
Scientists have examined the proteomes of 169 ovarian cancer patients to identify critical proteins expressed by their tumours...
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Landmark cancer research consortium announced
22 June 2016 | By Victoria White, Digital Content Producer
Four cancer centres in the US are coming together in a new consortium to accelerate the discovery and development of novel cancer therapeutics...
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DMD engineered muscle cells offer clues to genetic variations
26 May 2016 | By Victoria White, Digital Content Producer
Researchers have found a way to make human muscle cells bearing genetic mutations from people with Duchenne muscular dystrophy (DMD)...
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The risks of Zika pseudoscientific claims and conspiracy theories
24 May 2016 | By Victoria White, Digital Content Producer
Conspiracy theories and pseudoscientific claims refuting the facts around Zika virus vaccines could be putting people at risk, according to a new study...
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Mini-brain used to confirm Zika’s effect on foetal cortex
22 April 2016 | By Victoria White, Digital Content Producer
Studying a new type of lab-grown mini-brain, Johns Hopkins researchers have confirmed a key way in which Zika virus causes microcephaly...
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Researchers discover enzyme critical to telomere length
13 November 2015 | By Victoria White
The researchers say the new method they used to find the enzyme should speed discovery of other proteins and processes that determine telomere length...
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New high-throughput screening method could speed drug discovery
19 August 2015 | By Victoria White
Scientists have developed a potentially better and more accurate high-throughput screening technique and have used it to identify 24 drug candidates...
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Research identifies trigger responsible for regenerating hair and skin after trauma
11 August 2015 | By Katie Sadler, Digital Content Producer, Drug Target Review
Johns Hopkins researchers have identified a novel cell signalling pathway in mice through which mammals can regenerate hair and skin while healing from wounds. The discovery, summarised in an article published on 6th August in the journal Cell Stem Cell, could, they say, eventually help spur the growth of new…
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Nanoparticles used to breach lung mucus barrier
4 August 2015 | By Victoria White
Researchers have used nanoparticles to breach the human airway mucus barrier of lung tissue - a finding that could lead to effective drug delivery systems...
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New target may increase odds of successful mosquito-based malaria vaccine
16 June 2015 | By Victoria White
Researchers from the Johns Hopkins Bloomberg School of Public Health have located a new target for a potential vaccine against malaria...