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KLF14 gene may increase risk of type 2 diabetes
Scientists have identified a gene that in women is linked to the creation and location of new fat cells and therefore is thought to contribute to the risk of type 2 diabetes...
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King's College London
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How the study of lipidomics is benefiting from recent advances in mass spectrometry
There are no short-cuts in the complex field of lipidomics, explains Cristina Legido-Quigley, a Principal Investigator in Systems Medicine at Steno Diabetes Center Copenhagen in Denmark and at King’s College London.
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Scientists discover critical molecular biomarkers of preeclampsia
Small non-coding RNAs may be used to devise a diagnostic blood test for pregnant women...
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The spreading mechanism of malaria parasites provides new drug target
A team of researchers in the UK have discovered crucial new processes that allow malaria parasites to escape red blood cells and infect other cells, thus offering potential new treatment targets.
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Study reveals new mechanisms of cell death in neurodegenerative disorders
Researchers have discovered new mechanisms of cell death, which may be involved in debilitating neurodegenerative disorders...
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Chemo-boosting drug discovered for leukaemia
Drugs developed to treat heart and blood vessel problems could be used to treat leukaemia...
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New imaging technique may predict the of spread breast cancer
Researchers have developed a radioactive ‘tracer’ molecule to detect myeloid-derived suppressor cells’ accumulating in the lung in preparation for the arrival of breast cancer cells...
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£2m grant for University collaboration antibiotic resistance study
Dr Reda Lebcir from the University of Hertfordshire is part of an international team of researchers awarded a £2m grant from the ESRC (Economic and Social research Council).
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New research highlights key differences between mice and men
Research from King’s College in London, UK, and Lund University in Sweden could explain why diabetes drugs that have worked in animal experiments are not equally successful in humans. The researchers discovered differences – as well as hitherto unknown similarities – in the function of insulin-producing beta cells.
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Review: Biomarkers towards personalised therapy in cancer
Since the sequence of the human genome was published some 20 years ago, omics strategies have enabled the generation of detailed molecular signatures of cancers and their subtypes.
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Plasticell and Kings College London to collaborate in trials of blood platelet substitute
Over 10 million units of platelets are transfused worldwide each year in one of the most common procedures in clinical medicine. However, platelets derived from human donors can transmit infections and trigger serious immune reactions that eventually render the therapy ineffective (a condition known as alloimmune refractoriness). In addition, since…
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Stria vascularis ear structure discovery could lead to hearing loss treatment
24 August 2016 | By Niamh Louise Marriott, Digital Content Producer
The stria vascularis is essential for normal hearing and is involved in maintaining the endocochlear potential - a difference in charged molecules between compartments of the inner ear which act like a battery to power the transmission of sound signals from the ear to the brain...
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Genetic mutations linked to synchronous colorectal cancer found
5 July 2016 | By Victoria White, Digital Content Producer
A new study has identified genetic mutations affecting the immune system which may lead to the development of more than one colorectal cancer tumour at the same time...
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Cancer drugs successfully used to target uveitis
9 June 2016 | By Victoria White, Digital Content Producer
Drugs currently being trialled in cancer patients have been used to successfully target an autoimmune condition, uveitis, in mice...
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Explaining CAR T-cell therapy
23 March 2016 | By Dr John Maher, Principal Investigator, National Institute for Health Research (NIHR) Biomedical Research Centre (BRC) at Guy’s and St Thomas’ and Kings College London
Here, Dr John Maher of the NIHR BRC at Guy's and St Thomas' and Kings College London discusses CAR T-cell therapy and the exciting frontier the technique has opened up in the battle against cancer...