List view / Grid view

Mayo Clinic

news

Modelling the blood-brain barrier with organoids

22 May 2024 | By Drug Target Review

The world’s first generation of human BBB organoids from hPSCs accurately replicated features of cerebral cavernous malformation.

cancer cell next to a DNA strnd, idea of cancer genetic mutations

news

Senescent immune cells promote lung tumour growth

2 October 2023 | By Drug Target Review

A recent study sheds light on an unexpected discovery concerning macrophages, a vital type of white blood cell in the body's defence against infections and tumours.

news

Vaccine may reduce severity of long-haul covid symptoms

29 August 2023 | By Drug Target Review

Receiving a COVID-19 vaccination could offer a dual benefit by not only lowering the likelihood of developing long-haul COVID but also mitigating symptoms for individuals already dealing with this condition.

news

Molecular pathway shared by two neurodegenerative disorders found

3 March 2022 | By Ria Kakkad (Drug Target Review)

Scientists have gained deeper knowledge about the mislocalisation of a protein, providing a possible therapeutic target that could have implications in treating dementia.

Image showing broken bone / Osteoporosis on the spine

news

Study shows possible way to regenerate bones using messenger RNA

22 February 2022 | By Ria Kakkad (Drug Target Review)

Researchers at Mayo Clinic, US found that messenger RNA could be used at low doses to regenerate bones without side effects.

Woman with arthritus holding hand highlighted in red

news

Rheumatoid arthritis discovery may lead to novel inflammation blockers

24 November 2021 | By Anna Begley (Drug Target Review)

A new study links tumour necrosis factor seen in rheumatoid arthritis with T cell dysfunction, potentially leading to new therapies.

news

Gut microbiome linked to rheumatoid arthritis prognosis

15 September 2021 | By Anna Begley (Drug Target Review)

New genomic study reveals that the microbiome could predict rheumatoid arthritis prognosis, potentially advancing treatments.

news

Senolytic drugs reduce COVID-19 symptoms in mice, study shows

9 June 2021 | By Victoria Rees (Drug Target Review)

In pre-clinical studies, senolytic drugs were found to reduce inflammation and death from COVID-19 in older mice.

news

Purified exosomal product heals ischemic wounds in pre-clinical models

29 April 2021 | By Victoria Rees (Drug Target Review)

Researchers have found that ischemic wounds in pre-clinical models which were treated with a purified exosomal product were healed.

news

LEAP proton therapy could target cancer cells that resist treatment

18 February 2021 | By Victoria Rees (Drug Target Review)

A proton therapy that targets cancer cells which are resistant to treatment has shown success, sparing surrounding healthy cells.

3D rendering of a human torso with anatomically correct lungs highlighted in orange

news

T cells facilitate chronic lung injury in the elderly after viral infections, finds study

10 November 2020 | By Hannah Balfour (Drug Target Review)

After viral pneumonia in elderly mice, there is an accumulation of dysfunctional tissue-resident memory T cells in the lungs which scientists suggest may drive chronic inflammation and fibrosis.

cancer cell in yellow being attacked by white blobs - cancer drug/cell therapy

news

Study identifies potential therapeutic targets for most lethal pancreatic cancer

15 September 2020 | By Hannah Balfour (Drug Target Review)

The detailed analysis of adenosquamous cancer of the pancreas (ASCP) suggested FGFR and RORC were two promising therapeutic targets.

news

Study reveals how to make pancreatic cancer chemotherapy more effective

19 September 2019 | By Victoria Rees (Drug Target Review)

Researchers have shown that blocking a particular enzyme causes chemotherapy to become more effective against pancreatic cancers in pre-clinical studies.

news

Mutant form of Ebola could be used in vaccine development

17 September 2019 | By Victoria Rees (Drug Target Review)

A study has shown that a mutated form of the Ebola virus protects macaque models against the disease, demonstrating an opportunity for a drug target.

news

Reprogramming stem cells using the measles virus vector

15 February 2019 | By Iqra Farooq (Drug Target Review)

A method has been developed to reprogram stem cells using the measles virus vector, cutting a four-step process to only one stage...

Cookie	Type	Duration	Description
cookielawinfo-checkbox-advertising-targeting	persistent	1 year	The cookie is set by GDPR cookie consent to record the user consent for the cookies in the category "Advertising & Targeting".
cookielawinfo-checkbox-analytics	persistent	1 year	This cookie is set by GDPR Cookie Consent WordPress Plugin. The cookie is used to remember the user consent for the cookies under the category "Analytics".
cookielawinfo-checkbox-necessary	persistent	1 year	This cookie is set by GDPR Cookie Consent plugin. The cookie is used to store the user consent for the cookies in the category "Necessary".
cookielawinfo-checkbox-performance	persistent	1 year	This cookie is set by GDPR Cookie Consent WordPress Plugin. The cookie is used to remember the user consent for the cookies under the category "Performance".
PHPSESSID	session	1 year	This cookie is native to PHP applications. The cookie is used to store and identify a users' unique session ID for the purpose of managing user session on the website. The cookie is a session cookies and is deleted when all the browser windows are closed.
viewed_cookie_policy	persistent	1 year	The cookie is set by the GDPR Cookie Consent plugin and is used to store whether or not user has consented to the use of cookies. It does not store any personal data.
zmember_logged	session	1 year	This session cookie is served by our membership/subscription system and controls whether you are able to see content which is only available to logged in users.

Cookie	Type	Duration	Description
advanced_ads_browser_width	persistent	1 month	This cookie is set by Advanced Ads and measures the browser width.
advanced_ads_page_impressions	persistent	2 years	This cookie is set by Advanced Ads and measures the number of previous page impressions.
advanced_ads_pro_server_info	persistent	1 month	This cookie is set by Advanced Ads and sets geo-location, user role and user capabilities. It is used by cache busting in Advanced Ads Pro when the appropriate visitor conditions are used.
advanced_ads_pro_visitor_referrer	persistent	1 year	This cookie is set by Advanced Ads and sets the referrer URL.
bscookie	persistent	2 years	This cookie is a browser ID cookie set by LinkedIn share Buttons and ad tags.
IDE	persistent	2 years	This cookie is set by Google DoubleClick and stores information about how the user uses the website and any other advertisement before visiting the website. This is used to present users with ads that are relevant to them according to the user profile.
li_sugr	persistent	3 months	This cookie is set by LinkedIn and is used for tracking.
UserMatchHistory	persistent	1 month	This cookie is set by Linkedin and is used to track visitors on multiple websites, in order to present relevant advertisement based on the visitor's preferences.
VISITOR_INFO1_LIVE	persistent	5 months	This cookie is set by YouTube. Used to track the information of the embedded YouTube videos on a website.

Cookie	Type	Duration	Description
bcookie	persistent	2 years	This cookie is set by LinkedIn. The purpose of the cookie is to enable LinkedIn functionalities on the page.
GPS	persistent	30 minutes	This cookie is set by YouTube and registers a unique ID for tracking users based on their geographical location
lang	session	1 year	This cookie is set by LinkedIn and is used to store the language preferences of a user to serve up content in that stored language the next time user visit the website.
lidc	persistent	1 day	This cookie is set by LinkedIn and used for routing.
lissc	persistent	11 months	This cookie is set by LinkedIn share Buttons and ad tags.
vuid	persistent	2 years	We embed videos from our official Vimeo channel. When you press play, Vimeo will drop third party cookies to enable the video to play and to see how long a viewer has watched the video. This cookie does not track individuals.
wow.anonymousId	persistent	2 years	This cookie is set by Spotler and tracks an anonymous visitor ID.
wow.schedule	persistent	20 minutes	This cookie is set by Spotler and enables it to track the Load Balance Session Queue.
wow.session	persistent	20 minutes	This cookie is set by Spotler to track the Internet Information Services (IIS) session state.
wow.utmvalues	persistent	20 minutes	This cookie is set by Spotler and stores the UTM values for the session. UTM values are specific text strings that are appended to URLs that allow Communigator to track the URLs and the UTM values when they get clicked on.
_ga	persistent	2 years	This cookie is set by Google Analytics and is used to calculate visitor, session, campaign data and keep track of site usage for the site's analytics report. It stores information anonymously and assign a randomly generated number to identify unique visitors.
_gat	persistent	1 minute	This cookies is set by Google Universal Analytics to throttle the request rate to limit the collection of data on high traffic sites.
_gid	persistent	1 day	This cookie is set by Google Analytics and is used to store information of how visitors use a website and helps in creating an analytics report of how the website is doing. The data collected including the number visitors, the source where they have come from, and the pages visited in an anonymous form.

Cookie	Type	Duration	Description
cf_ob_info	persistent	1 minute	This cookie is set by Cloudflare content delivery network and, in conjunction with the cookie 'cf_use_ob', is used to determine whether it should continue serving “Always Online” until the cookie expires.
cf_use_ob	persistent	1 minute	This cookie is set by Cloudflare content delivery network and is used to determine whether it should continue serving “Always Online” until the cookie expires.
free_subscription_only	session	1 year	This session cookie is served by our membership/subscription system and controls which types of content you are able to access.
ls_smartpush	persistent	1 month	This cookie is set by Litespeed Server and allows the server to store settings to help improve performance of the site.
one_signal_sdk_db	persistent	Until cleared	This cookie is set by OneSignal push notifications and is used for storing user preferences in connection with their notification permission status.
YSC	session	1 year	This cookie is set by Youtube and is used to track the views of embedded videos.

Recommended

Mayo Clinic