Modelling the blood-brain barrier with organoids
The world’s first generation of human BBB organoids from hPSCs accurately replicated features of cerebral cavernous malformation.
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The world’s first generation of human BBB organoids from hPSCs accurately replicated features of cerebral cavernous malformation.
A recent study sheds light on an unexpected discovery concerning macrophages, a vital type of white blood cell in the body's defence against infections and tumours.
Receiving a COVID-19 vaccination could offer a dual benefit by not only lowering the likelihood of developing long-haul COVID but also mitigating symptoms for individuals already dealing with this condition.
Scientists have gained deeper knowledge about the mislocalisation of a protein, providing a possible therapeutic target that could have implications in treating dementia.
Researchers at Mayo Clinic, US found that messenger RNA could be used at low doses to regenerate bones without side effects.
A new study links tumour necrosis factor seen in rheumatoid arthritis with T cell dysfunction, potentially leading to new therapies.
New genomic study reveals that the microbiome could predict rheumatoid arthritis prognosis, potentially advancing treatments.
In pre-clinical studies, senolytic drugs were found to reduce inflammation and death from COVID-19 in older mice.
Researchers have found that ischemic wounds in pre-clinical models which were treated with a purified exosomal product were healed.
A proton therapy that targets cancer cells which are resistant to treatment has shown success, sparing surrounding healthy cells.
After viral pneumonia in elderly mice, there is an accumulation of dysfunctional tissue-resident memory T cells in the lungs which scientists suggest may drive chronic inflammation and fibrosis.
The detailed analysis of adenosquamous cancer of the pancreas (ASCP) suggested FGFR and RORC were two promising therapeutic targets.
Researchers have shown that blocking a particular enzyme causes chemotherapy to become more effective against pancreatic cancers in pre-clinical studies.
A study has shown that a mutated form of the Ebola virus protects macaque models against the disease, demonstrating an opportunity for a drug target.
A method has been developed to reprogram stem cells using the measles virus vector, cutting a four-step process to only one stage...