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Documenting the mammalian brain using machine learning
Novel approaches to brain disorder diagnosis and treatment may be developed following a project to form a map of the mouse hippocampus.
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MIT
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Breakthrough in breast cancer detection
MIT has unveiled a wearable ultrasound device. Ingeniously designed to seamlessly integrate into a bra, this innovative technology opens new avenues for early breast cancer diagnosis.
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Researchers discover the role of intestinal fibrosis in inflammatory bowel disease
The scientists used a new in vitro platform, which allowed intestinal organoids to be cultured on an open lumen, planar system that could be manipulated experimentally.
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New control system created for synthetic genes
MIT researchers have developed a technique that could help the production of monoclonal antibodies and other useful proteins.
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How neurons stimulate the brain’s microglia
A new MIT study highlights ailing neurons may activate an inflammatory response from the brain’s microglia immune cells.
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Researchers identify potential drugs to reduce COVID-19 mortalities
Researchers have established a list of compounds that effect cytokine storms that could reduce mortality in COVID-19 patients.
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The diversity of synthetic biology applications
Synthetic biology processes can be useful to therapeutic development, diagnostics and vaccine advancement. Drug Target Review’s Victoria Rees spoke with Dr Jim Collins, Termeer Professor of Medical Engineering & Science at MIT and Founding Core Faculty & Lead, Living Cellular Devices at the Wyss Institute at Harvard University, to explore…
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Molecular insights into LSCC may lead to new drug targets
New insights into lung squamous cell carcinoma (LSCC) have emerged from a proteogenomic study, leading to the identification of potential drug targets.
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Triple drug combination shows promise for pancreatic cancer treatment
MIT researchers have shown that a combination of three drugs can eliminate pancreatic tumours in mice, possibly leading to new therapies.
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Scientists develop synthetic cell that grows and divides uniformly
Researchers have created a single-celled synthetic organism able to grow and divide that could be used to produce drugs and detect disease.
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Machine learning calculates affinities of drug candidates and targets
A novel machine learning method called DeepBAR could accelerate drug discovery and protein engineering, researchers say.
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Antibodies from COVID-19 vaccines less effective against SARS-CoV-2 variants
Researchers have shown antibodies induced by the Pfizer and Moderna vaccines are less effective at neutralising certain SARS-CoV-2 variants.
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Machine learning identifies drugs to repurpose against COVID-19
A team has developed a machine learning approach to screen for and identify drugs that could be repurposed against COVID-19 in the elderly.
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Could metabo-oncology be the treatment modality of the future?
Jim Shanahan from SynDevRx explains why metabo-oncology treatment modalities could be the answer to a rise in metabolic disorders and cancers.
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“Organs-on-a-chip” reveal how digestive tract may influence neurological disease
A team has used their new organs-on-a-chip system to replicate the interactions between the brain, liver and colon.