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Moderna

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mRNA vaccine provides enhanced protection against mpox

6 September 2024 | By Drug Target Review

The mRNA vaccine candidate more effectively limited symptoms and disease duration in non-human primates.

article

Is an HIV vaccine on the horizon?

10 October 2022 | By Victoria Rees (Drug Target Review)

Researchers in the US have developed a potential HIV vaccine approach that aims to prompt the creation of broadly neutralising antibodies via mRNA.

news

Antibodies that can neutralise SARS-CoV-2 Omicron variant identified

5 January 2022 | By Victoria Rees (Drug Target Review)

A study has revealed four classes of antibodies that can neutralise Omicron by targeting one of four areas of the spike protein present in SARS-CoV-2 variants.

Man holding paper with DNA molecule breaking apart, representing gene editing

news

Moderna and Metagenomi to develop in vivo gene therapies

3 November 2021 | By Anna Begley (Drug Target Review)

Moderna and Metagenomi have announced a collaboration to jointly create next-generation in vivo gene editing therapeutics.

article

The diversity of synthetic biology applications

23 September 2021 | By Dr Jim Collins (MIT)

Synthetic biology processes can be useful to therapeutic development, diagnostics and vaccine advancement. Drug Target Review’s Victoria Rees spoke with Dr Jim Collins, Termeer Professor of Medical Engineering & Science at MIT and Founding Core Faculty & Lead, Living Cellular Devices at the Wyss Institute at Harvard University, to explore…

article

Protecting liposomes in COVID-19 mRNA vaccines could increase their stability

27 April 2021 | By Victoria Rees (Drug Target Review)

A team from the University of Texas at Dallas has shown that a novel buffer solution is effective at stabilising the liposomes and lipid nanoparticles in certain COVID-19 vaccines.

article

Neuropilin-1: a key receptor in SARS-CoV-2 infection

27 November 2020 | By Nikki Withers (Drug Target Review)

Results of a recent study by researchers at the University of Bristol indicate neuropilin-1 is an important host factor for SARS-CoV-2 infection. The team suggests that blocking neuropilin-1 may be a valuable therapeutic intervention in the treatment of COVID-19. Nikki Withers spoke to one of the study’s lead investigators, Dr…

article

Treating cytokine storms in COVID-19 patients

23 October 2020 | By Dr Fiona McCann (CannBioRx Life Sciences), Dr H Michael Shepard (Enosi Life Sciences), Sir Marc Feldmann (Enosi Life Sciences)

Enosi Life Science researchers Sir Marc Feldmann, Dr H Michael Shepard and Dr Fiona McCann explain why anti-TNF therapies may be effective in treating COVID-19 associated cytokine storms and other inflammatory conditions.

article

Coronavirus update: COVID-19 vaccine pre-clinical developments

5 August 2020 | By Victoria Rees (Drug Target Review)

Drug Target Review rounds up some of the latest news in COVID-19 vaccine candidate R&D.

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