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How the DA subtype of Wilms tumour resists chemotherapy
Researchers suggest that DA histology slowly emerges by accumulating burdens of DNA damage and copy number aberrations.
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Nagoya University
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New technique to extract and analyse extracellular vesicles
Cellulose nanofiber sheets enable analysis of EVs, and miRNAs within them, offering potential for cancer treatment and personalised medicine.
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New biomarker advances cancer treatments
Researchers have discovered ways to enhance NIR-PIT to ensure tumours are treated sufficiently and improve patient outcomes.
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Pure capped mRNA vaccine encourages more effective vaccine development
Japanese researchers have designed a pure capped mRNA vaccine which has shown a better protein production in the immune system.
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Scientists inhibit cancer cell growth using pyrrolizidine alkaloid
Researchers in Japan have succeeded in inhibiting cancer cell growth using pyrrolizidine alkaloid, a component of plant origin previously thought to be too toxic to administer.
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Researchers engineer protein assembly via artificial protein needles
Japanese researchers have formed ordered biological structures using protein needles, enabling protein self-assembly into lattice structures.
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Altering balance of fibroblasts could prevent spread of colorectal cancer
Researchers have found that colorectal cancer-associated fibroblasts can be altered using a gremlin 1-neutralising antibody or by overexpressing meflin.
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Two compounds identified as circadian clock modulators
Researchers have developed two small molecules which target two components of the circadian rhythm and could be used to lengthen the body clock.
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New protein function could be key to treatment of drug addiction
Scientists have revealed new findings about the neural circuit involved in the reward stimulus, which plays a major role in drug dependence and psychological disorders.
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Cancer-suppressing cells identified in pancreatic cancer
Cells containing Meflin play a role in restraining the progression of pancreatic cancer and could lead to new therapies against the disease.
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Five newest developments for imaging in drug research
Imaging methods are used by scientists to identify therapeutic targets and improve drug efficacy. This article lists five of the latest developments for imaging techniques.