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Alpha-4 beta-7 protein levels linked to HIV infection risk
Scientists have shown a relationship between the proportion of key immune cells that display high levels of alpha-4 beta-7 at the time of HIV infection and health outcomes...
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National Institutes of Health (NIH)
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Statistical computing tool visualises employment trends in biomedical science
Scientists looking for jobs after completing their training may soon have a new tool that helps them evaluate various career paths...
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Research enables screening millions of human antibodies for new drug discovery
Researchers have outlined a pioneering method of screening a person’s diverse set of antibodies for rapid therapeutic discovery.
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New study offers insights on genetic indicators of COPD risk
Researchers have discovered that genetic variations in the anatomy of the lungs could serve as indicators to help identify people who are particularly at risk for COPD...
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NIH researchers report first 3D structure of DHHC enzymes
The 3D structure of DHHC proteins has been detailed for the first time, explaining how they function and potentially offering a blueprint for designing therapeutic drugs.
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Stem cell therapy discovery for age-related macular degeneration
Stem cell-derived retinal cells need primary cilia to support the survival of light-sensing photoreceptors...
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RT-QuIC testing detects prion protein in the skin of CJD patients
Scientists have detected abnormal prion protein in the skin of patients that have died from Creutzfeldt-Jakob disease...
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NIH study identifies new targets for anti-malaria drugs
Researchers have sought to uncover the role of plasmepsins IX and X, produced by P. falciparum for metabolic processes...
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Three-in-one antibody may protect from HIV-like virus
A three-pronged antibody has been found to protect from infection with two strains of SHIV, better than individual natural antibodies...
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Flow cytometry – accelerating neuroscience research
Flow cytometry continues to evolve at a fast pace and provides neuroscientists with the ability to perform many highly-specialised assays simultaneously. It meets the demands of cutting-edge research in neuroscience that has allowed researchers to isolate particular neural cells from heterogeneous population and catalogue its molecular or physical features...
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NGS: empowering infectious disease research beyond reality
Pushpanathan Muthuirulan & Pooja Sharma explain how high-throughput next-generation sequencing (NGS) technologies are revolutionising our ability to characterise infectious diseases at genomic, transcriptomic and epigenetic levels...
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Sequencing all 24 human chromosomes uncovers rare disorders
Study from NIH may help improve prenatal genetic screening...
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Bacterial antibiotic resistance pathways identified
Researchers have described two structures and mechanisms - efflux pumps and reinforced cell walls - that certain disease-causing bacteria use to keep antibiotics away...
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US Phase 2 trial to test targeted drugs in paediatric tumours
Phase 2 trial to explore targeted therapies for children with solid tumours that harbour specific genetic mutations which have progressed during or after standard therapy...
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Researchers use smartphone data in global study of physical activity
Researchers at Stanford University in Palo Alto, California, have tracked physical activity by population for more than 100 countries.