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Researchers use smartphone data in global study of physical activity
Researchers at Stanford University in Palo Alto, California, have tracked physical activity by population for more than 100 countries.
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National Institutes of Health (NIH)
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Study asks if mistaken antibodies led research down 20-year dead end
For nearly two decades researchers have sought a way to target an oestrogen receptor in the hope they could improve breast cancer survival, but an article contends that the effort may never pan out.
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Scientists identify single-gene mutations that lead to eczema
NIH-supported research suggests potential treatment strategy following the identification of single-gene mutations that lead to eczema.
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Plant-Mediated Modulation of Reactive Oxygen Species (ROS) Homeostasis
A review of Keap1/Nrf2 modulation of ROS homeostasis, and its pivotal role in the pathogenesis of cancer, Type 2 diabetes mellitus & neurological disorders.
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Researchers identify a key controller of biological machinery in cell’s ‘antenna’
St. Jude Children’s Research Hospital discovery of a regulatory enzyme working at the primary cilium could lead to treatments for the brain tumour medulloblastoma.
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Scientists jump hurdle in HIV vaccine design
Scientists at The Scripps Research Institute (TSRI) have made another important advance in HIV vaccine design.
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Researchers find key molecule that could lead to new anaemia therapies
Researchers find key molecule that could lead to new therapies for anaemia and other iron disorders.
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Scientists light the way for immune system to attack cancer
The science behind harnessing the immune system to fight cancer is complicated, but a University of Rochester Medical Center laboratory discovered a simple, practical way to use light and optics to steer killer immune cells toward tumours.
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Dartmouth tuberculosis vaccine passes important milestone
Investigators at Dartmouth's Geisel School of Medicine announced that two new studies of DAR-901, their investigational vaccine against tuberculosis (TB), have moved it to the forefront of new vaccines in development for global control of this deadly infectious disease.
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Pluristem’s post nuclear exposure study in primates a success
Pluristem Therapeutics announced the promising results of its non-human primates (NHP) pilot study for PLX-R18 as a treatment for Acute Radiation Syndrome (ARS).
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Assays In-Depth Focus 2017
HTS can be carried out in a number of formats, ranging from simple biochemical (target-based) to whole animal screening assay formats. Horst Flotow, from Hit Discovery Constance, discusses the benefits and practicalities of, and recent progress in, whole animal screening. Madhu Lal-Nag, National Center for Advancing Translational Sciences, and Anton…
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How Ketamine could cure depression
Amorsa Therapeutics' CSO, Michael Palfreyman, discusses how the party drug Ketamine can be used to target NMDA receptors and treat depression...
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TSRI scientists use ligands to turbocharge drug discovery
Ligands are useful tools for studying how proteins work in cells and could lead to the development of new drugs.
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Molecule activates pain relief and prevents high during medical marijuana use
Medicinal marijuana is used frequently as a painkiller for a variety of ailments and diseases yet its psycho active side effects are seen by many as a significant disadvantage.
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TSRI’s rat study shows how brain stores memories
A new study led by scientists at the Scripps Research Institute (TSRI) sheds light on how the brain stores memories.
