news Lupus flare-ups linked to bacterial growth in gut 29 June 2023 | By Izzy Wood (Drug Target Review) US researchers find that recurrent bouts of systemic lupus erythematosus is closely tracked with measurable upticks in growth in the gut of a certain species of bacteria.
news What is the key source of T cell exhaustion? 22 March 2023 | By Izzy Wood (Drug Target Review) US discovery opens the way to drugs that can prevent T cell therapies from losing their potency over time.
news Synthetic antibody treats congenital myasthenia in mice 28 June 2021 | By Victoria Rees (Drug Target Review) Researchers have designed an antibody that attaches to MuSK, which prevented early lethality of mice with congenital myasthenia.
news New class of compounds found to block coronavirus reproduction 24 June 2021 | By Victoria Rees (Drug Target Review) In cell cultures, a compound named STM2457 was shown to interfere with coronavirus replication, making it a potential treatment for SARS-CoV-2.
news IL-1β produced by pancreatic cancer cells suppresses immune attack on tumours 10 January 2020 | By Hannah Balfour (Drug Target Review) Researchers have discovered that pancreatic cancer cells secrete IL-1β to suppress the immune system and suggest antibody treatments as a therapy for pancreatic ductal adenocarcinoma.