Okinawa Institute of Science and Technology (OIST)

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How a dynein subunit maintains neuronal health

9 November 2023 | By Ellen Capon (Drug Target Review)

Understanding how a molecular transport system inside neurons works could be used for therapeutic approaches to neurodegenerative disease.

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Drug Target Review’s top content picks from 2022

13 December 2022 | By Izzy Wood (Drug Target Review), Ria Kakkad (Drug Target Review)

In this article, Drug Target Review’s Izzy Wood and Ria Kakkad share some of the most ground-breaking moments from drug discovery this year.

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Targeting tau – chasing a treatment for Alzheimer’s

22 September 2022 | By Victoria Rees (Drug Target Review)

Alzheimer’s disease remains one of the largest challenges for the global ageing population. In this article, Victoria Rees, Editor of Drug Target Review, reviews some of the latest research, highlighting how progress has been made in understanding tau as well as how to potentially target this protein as a therapeutic strategy against…

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Study reveals how tau impairs communication between neurons in Alzheimer’s

21 September 2022 | By Victoria Rees (Drug Target Review)

A new study has shown how tau weakens transmission across synapses in the brains of mice, providing insight into Alzheimer's.