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Osaka University

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Naphthyridine-Azaquinolone reverses Huntington’s DNA repeats in mouse model

28 February 2020 | By Hannah Balfour (Drug Target Review)

Researchers show Naphthyridine-Azaquinolone (NA) could be a possible future therapy able to slow the progression and improve the symptoms of Huntington’s disease.

news

DNA successfully cut and inserted using Class 1 CRISPR system

10 December 2019 | By Rachael Harper (Drug Target Review)

A new study has shown that a Class 1 CRISPR gene editing system can achieve functional DNA repairs in human cells with no prominent off-target effects.

article

Five recent Parkinson’s disease drug target discoveries

10 September 2019 | By Victoria Rees (Drug Target Review)

This article highlights five of the latest findings that could be used in the development or design of new therapies to treat Parkinson’s disease.

news

Taking a BiTE out of lung cancer

22 February 2019 | By Iqra Farooq (Drug Target Review)

Bispecific T-cell engager technology (BiTE) could be used to quickly and accurately diagnose patients suffering from lung cancer...

news

Nanopore detection of single flu viruses to control influenza outbreaks

22 November 2018 | By Drug Target Review

Osaka University researchers have developed a method using single-particle nanopore sensors and AI to detect single influenza virions...

news

Experimental vaccine could replace aspirin

29 October 2018 | By Drug Target Review

An experimental vaccine tested on mice could one day replace common blood thinners that are taken orally, such as aspirin...

news

Dectin-1 pathway may be crucial for treating fungal inflammation and pain

30 August 2018 | By Iqra Farooq (Drug Target Review)

Researchers have identified the dectin-1 pathway as being a potential target for the treatment of pain associated with candidiasis...

news

Researchers uncover origin of virus-fighting plasma B cells

19 April 2018 | By Drug Target Review

A group of researchers have discovered an important mechanism that governs how B cells are chosen to become plasma cells...

Helpful B cells lend a hand to developing neurons

news

Helpful B cells lend a hand to developing neurons

16 March 2018 | By Drug Target Review

Researchers at Osaka University have identified an immune cell that promotes the growth of neuron-supporting cells in the developing mouse brain.

news

Scientists develop green fluorescent protein to aid intracellular research

9 January 2018 | By Drug Target Review

Researchers at Osaka University in Japan have developed a superior acid-tolerant green fluorescent protein to enhance the study of intracellular molecular dynamics.

news

New drug targets for a rare kidney and liver disease

24 August 2017 | By Dr Zara Kassam (Drug Target Review)

In a joint international study, researchers have collaborated to uncover how mutations in a single gene called PKHD1 lead to symptoms associated with a rare kidney and liver disease...

news

The immune system promotes spontaneous heart regeneration

1 June 2017 | By Niamh Marriott (Drug Target Review)

In adult mammal hearts, cardiomyoctyes do not proliferate following damage, like that caused by myocardial infarction.

news

Muscle cryomicroscopy images could provide model for nanomachines

9 March 2017 | By Osaka University

Myosin provides model for nanomachines

Chugai and IFReC provide top level Japanese collaboration to benefit

news

Chugai and IFReC provide top level Japanese collaboration to benefit immunology

20 May 2016 | By Mandy Parrett, Editorial Assistant

Osaka University and Chugai Pharmaceutical Co., Ltd. announce details of their collaborative agreement for advanced research into immunology.

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