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16 December 2021 | By Eurofins DiscoverX and Sanford Burnham Prebys Medical Discovery Institute
Watch this on-demand webinar to learn about orphan GPCRs as drug targets and the challenges related to lead identification.
A protein called PPP1R1B has been revealed as a drug target for pancreatic cancer as it stopped the metastasis of tumours in mice.
After screening 12,000 existing drugs, scientists have identified 21 which prevent the replication of SARS-CoV-2 in concentrations safe for patients.
Scientists demonstrate that vitronectin is responsible of the formation of deposits in dry age-related macular degeneration and suggest inhibitors could slow disease progression.
A new study has revealed that the Siah2 protein is crucial to control Tregs in mice, which can reduce the effectiveness of immunotherapies.
This article highlights some of the most recent drug target discoveries that could be used to develop and design a treatment for pancreatic cancer.
A machine-learning algorithm has been created that automates high-throughput screens of epigenetic medicines.
Sanford Prebys Medical Discovery Institute (SBP) researchers recently discovered an alternative metabolic pathway that might be used by cancer cells to survive nutrient deprivation.
Scientists in the United States have investigated the relationship between tumour suppressor, protein kinase C zeta (PKC zeta), and metastatic colorectal cancer.
A team of scientists in the United States has identified a mechanism that explains the development of hyperaldosteronism. These findings offer a potential path for drug discovery to treat the condition, which often leads to secondary hypertension.
Researchers have identified a new protective function for a brain protein genetically linked to Alzheimer's...
Researchers have developed a proof-of-concept nano-system that dramatically improves the visualisation of tumours...
28 September 2016 | By Niamh Louise Marriott, Digital Content Producer
During anthrax infections, the bacterium Bacillus anthracis secretes a toxin consisting of two related enzymes named lethal factor and edema factor...
