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Study shows how cone cells in the retina form connections with brain
Researchers have discovered how cone cells in the retina send information to the brain, which could be used in the development of treatments for blindness.
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Researchers emphasise importance of antigen valency for vaccine efficacy
Researchers have shown that factoring in valency to vaccine design can improve the number of antibody binding sites on an antigen.
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Study shows heart repair factor boosted by RNA-targeting compound
Researchers have discovered compounds able to restart production of VEGF-A in cellular models, which rebuilds blood vessels and muscle in damaged heart tissue.
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Method to synthetically produce terpenes developed by researchers
Scientists have developed a synthetic biology process using enzymes to create three families of terpenes, potential starting points for new drugs.
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Atomic-scale details of SARS-CoV-2 Spike protein from vaccine obtained
The SARS-CoV-2 Spike protein from a COVID-19 vaccine candidate has been characterised by researchers, supporting the neutralising antibody response it elicits.
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“Potent” antibodies provide protection from COVID-19 in cell cultures, finds study
Newly discovered antibodies found in the blood of recovered COVID-19 patients could provide robust protection against SARS-CoV-2, say researchers.
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Researchers reveal how SARS antibody binds to COVID-19 coronavirus
The interaction between a SARS antibody called CR3022 and the COVID-19 coronavirus has been mapped by researchers, revealing a viral vulnerability.
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AI technology to screen existing drugs for use against COVID-19
A collaboration aims to utilise a compound library of 15,000 clinically-ready molecules and screen then against three COVID-19 targets.
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Novel technique creates complex synthetic drug molecules
A new method has been developed by researchers to create synthetic molecules which replicate natural structures and have potential medicinal uses.
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Industry collaborate to screen existing drugs to repurpose for cystic fibrosis
In an effort to address some of the more serious untreatable infections encountered by patients with cystic fibrosis, Calibr will collaborate with the Cystic Fibrosis Foundation on a two-year project.
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Screening platform reveals compounds that protect neuronal mitochondria
Researchers have developed a screening system and identified a set of compounds that protect neuronal mitochondria in mice.
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RNA-targeting strategy can block Parkinson’s disease driver
A new drug-like compound has been developed which reportedly prevents the body from producing a protein that is often at the root of Parkinson's disease.
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Experimental HIV vaccine induces bnAb production in models
Researchers have developed a vaccine for HIV that has shown success in rabbits, by neutralising a wide range of HIV strains using bnAbs.
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Newly-discovered protein could play key role in fighting obesity
An unexpected finding about a protein that's highly expressed in fat tissue could lead to new approaches for addressing obesity and many other diseases.
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New HIV vaccine candidate design developed by researchers
A study has demonstrated a novel vaccine design in mice which could be used to immunise patients against HIV.