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How tumours prevent formation of immune responses
Scientists found that preventing the effects of prostaglandin E2 could be an effective therapy to overcome tumour defence.
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Technical University of Munich (TUM)
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Immunotherapy: antibody set for combating tumours
A recent study sheds light on the potential of artificial DNA structures that, when combined with antibodies, guide the immune system to target cancer cells specifically.
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New organoid emulates development of the human heart
The team are the first researchers in the world to successfully create an organoid containing both heart muscle cells and cells of the outer layer of the heart wall.
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Novel synthetic peptides could suppress formation of harmful amyloid aggregates
German researchers have designed peptides that bind to amyloidogenic proteins linked to Alzheimer’s and type 2 diabetes, to effectively suppress both cytotoxic amyloid aggregation and amyloid cross-accelerating interactions.
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New research could help find a therapy to treat COVID-19
Researchers from the Technical University of Munich have successfully used specific enzymes to destroy the genetic information of SARS-CoV-2 directly after the virus enters a cell.
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Innovative algorithm could help advance single-cell genomics
Researchers have developed a novel algorithm, “scArches”, that can compare data on single-cell genomics to better understand diseases.
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Synthetic peptides block atherosclerosis in pre-clinical studies
Researchers have synthesised peptides that function like a soluble chemokine receptor, blocking atherosclerosis in animal models.
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SARS-CoV-2 also uses neuropilin-1 to infect human cells
Researchers reveal that SARS-CoV-2 is more infectious than SARS-CoV because it can use both ACE2 and neuropilin-1 to infect cells.
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Artificial binding protein could be developed into a novel anti-viral or cancer therapy
Scientists have created an artificial protein able to recognise and bind cell surface carbohydrates with high affinity and selectivity.
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Novel label-free method enables imaging of metabolites
A label-free imaging technology has been developed by researchers, allowing them to investigate biomolecules such as metabolites, aiding in the study of drugs.
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Direct toxic action of beta-amyloid in Alzheimer’s patients identified
The cause and trigger of the large clumps of protein beta-amyloid found in the brains of early-stage Alzheimer's patients have been discovered.
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Using AI for error correction in single cell analyses
Researchers have developed algorithms that make it possible to predict and correct cells to identify genes...
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Administering hormones affects DNA
In an experiment with pigs, researchers have demonstrated for the first time that the administration of even extremely low doses of an endocrine disruptor - in this case, an endogenous oestrogen - leads to epigenetic changes in a pregnant sow’s DNA.
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PSMA PET/CT imaging provides precision radiation therapy for prostate cancer
A nuclear medicine scan may locate prostate cancer recurrence after radical prostatectomy early after disease recurrence and could help guide salvage radiotherapy...
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Proteome of the human heart mapped for the first time
Researchers have compiled an atlas of the heart to identify differences between healthy and diseased cells...