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Slc4a4 restores normal brain function after ischemic stroke
Researchers have elucidated how Slc4a4 governs astrocyte-endothelial cell interaction in blood-brain barrier maintenance and repair.
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Investigating the inflammatory myocardial microenvironment
By studying the molecular cell states within transplanted paediatric hearts, researchers have unlocked new treatment strategies.
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A new way to visualise sensory neurons
US researchers have uncovered a novel method using a tool used to visualise ion channels in mechanosensory neurons.
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Drug target for spinocerebellar ataxia type 1 identified by researchers
A team has found that a mutation in the ATAXIN-1 gene causes spinocerebellar ataxia type 1 (SCA1), presenting a drug target for the condition.
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Using scientific literature to aid the development of a safe and effective COVID-19 vaccine
Researchers in the US describe how they utilised previously published scientific literature to guide the design of their potential COVID-19 vaccine.
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Alzheimer’s disease linked to tau-mediated RNA splicing errors
A new study has shown the possibility of using RNA splicing as a potential molecular target for Alzheimer's disease.
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HER2-targeted CAR T-cell therapy shows promise in patients with sarcoma
A combination of chemotherapy and chimeric antigen receptor (CAR) T cells designed to target the protein HER2 was found to be safe and showed clinical responses in paediatric and adult patients with advanced HER2-positive sarcoma...
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Protein mTOR regulated by Src in cancer growth
Researchers at Baylor College of Medicine and Texas Children's Hospital have identified a connection between cancer proteins mTORC1 and Src...
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New evidence sheds light on how Parkinson’s disease may happen
Researchers at Baylor College of Medicine and Texas Children’s Hospital have identified unexpected new key players in the development of an early onset form of Parkinson’s disease called Parkinsonism.
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OTUD7A gene identified as key player in 15q13.3 microdeletion syndrome
Researchers have identified in a mouse model OTUD7A as the gene that accounts for many characteristics of 15q13.3 microdeletion syndrome...