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How MMR-deficient colorectal cancers regulate their growth

9 July 2024 | By Ellen Capon (Drug Target Review)

Understanding how MMR-deficient colorectal cancers drive tumour growth and avoid immune detection could pave the way for personalised cancer medicine.

news

New biological pathway in IBD discovered

6 June 2024 | By Drug Target Review

Researchers have identified a new biological pathway driving IBD and similar conditions that could be targeted with MEK inhibitors.

news

New single-cell lipidomics method may unlock cancer treatments

24 April 2024 | By Drug Target Review

A new method for a fragmentation-based identification of lipids could enable the study of cancer cells in detail not seen before.

Women scientists nurses and doctors fighting against coronavirus. Feminist steminist illustration. Female Doctors, nurses and scientists together.

article

Women in STEM with Lindsey Clarke: ‘everyone has half an hour’

8 March 2023 | By Izzy Wood (Drug Target Review)

For International Women's Day, Drug Target Review’s Izzy Wood recently spoke to Lindsey Clarke about her experience as a woman in STEM.

article

Five recent CRISPR drug target discoveries

21 November 2022 | By Izzy Wood (Drug Target Review)

This article highlights five of the latest findings revealed using CRISPR that could be used in the development or design of new therapies.

news

Replication proteins a potential new target for COVID-19 vaccines

12 November 2021 | By Anna Begley (Drug Target Review)

A new study claims that future COVID-19 vaccines should activate T cells to attack infected cells expressing replication proteins.

news

DNA mechanism discovery may open up Huntington’s disease therapies

1 September 2021 | By Anna Begley (Drug Target Review)

Scientists unveiled how a DNA repair protein may prevent Huntington’s disease, presenting a new target in future therapies.

news

Key hallmark of ALS is successfully reversed in laboratory

9 August 2021 | By Anna Begley (Drug Target Review)

Scientists demonstrated how to reverse the incorrect localisation of three RNA-binding proteins in ALS, potentially leading to treatments.

Single cancer cells in lab grown tumours analysed with new technology

news

Single cancer cells in lab-grown tumours analysed with new technology

21 February 2020 | By Rachael Harper (Drug Target Review)

New technology is for the first time enabling scientists to analyse the individual behaviour of millions of different cells living inside lab-grown tumours, which could lead to new personalised cancer treatments.

Scientists can now 'listen in' on cancer cells with new technique

news

Scientists can now ‘listen in’ on cancer cells with new technique

19 February 2020 | By Rachael Harper (Drug Target Review)

More effective drugs could be developed due to a new technique that has allowed scientists to decipher how millions of individual cells are communicating with each other on miniature tumours grown in a lab.

news

Catching lung cancer early using molecular profiling

22 January 2019 | By Iqra Farooq (Drug Target Review)

Researchers have identified how they can differentiate between lesions in the airways that are benign and those that could become cancerous...

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