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Scientists discover new clue for platelet activation to target thrombosis
Researchers have revealed a novel mechanism for platelet activation, suggesting a potential target for antithrombotic therapy.
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Birmingham University
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Licensed drug may reduce COVID-19 infection by 70 percent
Fenofibrate and its active form, fenofibric acid, have been shown to significantly reduce COVID-19 infection in human cells.
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A new role for an old immune cell may lead to novel therapies
A new study has identified a previously undescribed role for a type of unconventional T cell with the potential to be used in the development of new therapies for infection and cancer.
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Elevating brain protein allays Alzheimer’s symptoms and improves memory
25 August 2016 | By Niamh Louise Marriott, Digital Content Producer
The protein, called neuregulin-1, has many forms and functions across the brain and is already a potential target for brain disorders such as Alzheimer's disease, amyotrophic lateral sclerosis and schizophrenia...
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Early intervention could prevent myeloma from taking root
11 July 2016 | By Victoria White, Digital Content Producer
Researchers from the University of Birmingham have revealed how a common condition called ‘MGUS’ can develop into myeloma...
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Omics In-Depth Focus 2016
Featured in this Omics In-depth Focus: The next revolution in stratified medicine-molecular phenotyping with metabolomics; Pharmacometabolomics as the key to personalised medicine...
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Novel anti-diabetic drugs that can be controlled with light
11 April 2016 | By Victoria White, Digital Content Producer
New research could pave the way for a new generation of anti-diabetic drugs that are activated by the presence of either blue or ultra-violet light...
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Project launched for CAR-T cell immuno-oncology therapy development
6 January 2016 | By Victoria White
The Cell Therapy Catapult, the University of Birmingham and Cancer Research Technology have launched the project to develop a new immuno-oncology cellular therapy based on gene modifying T-cells to target solid tumours...
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Next-generation transcriptomic analysis in cancer vascular research
Over the past decade significant advances have been made in the fields of genomic and transcriptomic profiling, inspired by the advent of next-generation sequencing (NGS). Yet despite the considerable promise of these new technologies, uptake has been slow. The focus of this review is the use of next-generation transcriptomic analysis…
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Researchers win EBF funding to advance Wolfram syndrome project
8 September 2015 | By Victoria White
A University of Birmingham research team, developing a treatment for Wolfram Syndrome, has secured £17,000 from the Enterprising Birmingham Fund...
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Neuroblastoma cells drain immune system’s batteries
3 August 2015 | By Victoria White
Cancer cells in neuroblastoma contain a molecule that breaks down a key energy source for immune cells, leaving them too drained to fight the disease...
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Contraceptive and cholesterol-lowering drug combination (BaP) used to treat cancer
15 May 2015 | By Victoria White
The BaP combination of a cholesterol-lowering drug, bezafibrate and a contraceptive steroid could be an effective treatment for a range of cancers.