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Mutation in n-Tr20 gene found to disrupt neurotransmission in brain
Researchers have shown that a mutation in the n-Tr20 gene can alter brain function and behaviour, while loss of the gene made mice resistant to seizures.
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University of California San Diego
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Antisense oligonucleotide treatment cures Parkinson’s disease in mice
By administering a one-time PTB antisense oligonucleotide therapy to mice, researchers observed an increase in neurons and elimination of Parkinson's from the models.
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Decoy nanoparticles show success in cell cultures as COVID-19 therapy
Researchers have developed 'nanosponges' cloaked in lung cell membranes and macrophage membranes which they found could attract and neutralise COVID-19 in cell cultures.
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Researchers gain new insight into LRRK2 – a potential cause of Parkinson’s
Scientists in the US have applied a novel technique to finally unravel a particular kinase enzyme that is associated with familial Parkinson’s disease; providing a clearer potential therapeutic target.
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Metal-based fragment molecule library to screen for drug candidates
Researchers have developed a novel metal-based fragment library of molecules that can be used to screen for new drug candidates.
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Vital cell metabolic pathway regulator identified by study
A study has revealed that the mitoNEET protein controls a metabolic and functional gateway on mitochondria, which could provide a drug target for cancer.
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Key step in the transformation of B-cells to antibody-secreting cells described
Scientists have detailed the role of a key controlling factor in the transformation of B-cells into antibody-secreting cells.
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Editing enzyme could promote tumour suppressor loss
The detection of 'copy editing' by a stem cell enzyme in over 20 tumour types could be a biomarker and possible therapeutic target for certain cancers...
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Algorithm to more effectively identify antibiotic compounds
An international team of scientists has developed a candidate identification technique in the form of an algorithm that reduces the chances of rediscovering known compounds.
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NDF identified as the missing factor in gene activation
Scientists find the missing factor in gene activation...
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Computational method speeds hunt for new antibiotics
New algorithm reduces search time from hundreds of years to mere hours...
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Researchers develop a remote-controlled cancer immunotherapy system
Researchers have developed an ultrasound-based system that can non-invasively and remotely control genetic processes in live immune T cells so that they recognise and kill cancer cells.
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Pancreatic cancer: specific protein promotes development of pancreatitis and tumours
A study has shown that disruption to cell autophagy is involved in the development of pancreatic cancer.
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Tumour environment found to trigger cells to metastasize
The environment surrounding a tumour can trigger metastatic behaviour in cancer cells...
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Scientists create “tracking” nanoagents to illuminate very small diseased tissues
Polymer nanoagents that can ‘light up’ tiny areas of diseased tissues that conventional methods fail to detect, have been created by a research team led by NTU Singapore.