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Mechanism linking obesity to inflammation uncovered
This study is first to demonstrate with statistical certainty that human visceral adipose tissue accumulated in the abdominal cavity secretes more extracellular vesicles.
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University of Eastern Finland
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New research sheds light on what influences target protein binding time
The length of time that drug molecules attach to their target protein varies greatly and impacts the protein’s behaviour and drug efficacy. In a new study, scientists in Finland have identified some causal factors for this variance, with the hope it will bring clarity for drug developers.
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Getting “under the skin” of frontotemporal dementia
Researchers at the University of East Finland have been using skin cells to investigate pathological hallmarks in frontotemporal dementia patients.
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Astrocytes likely contribute to Parkinson’s disease progression
A new study shows astrocytes derived from monogenic Parkinson’s patients have metabolic alterations that mean they could be contributing to disease progression.
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New variant of the GLA gene to be linked with Fabry cardiomyopathy
A study in Finland has found a strong connection between the A143T variant of the GLA gene and increased risk of Fabry cardiomyopathy, which affects the heart, kidneys and nervous system.
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Two new retinal pigment epithelial cell models developed
Researchers have created two new cellular models that can be used in the study of ocular diseases and drug testing.
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T-cell subset association with type 1 diabetes demonstrated by study
A new study from the University of Eastern Finland has shown that peripheral T helper cells may have a role in the development of type 1 diabetes.
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Antibacterial compounds focusing on LsrK kinase
Researchers at the University of Eastern Finland have developed antibacterial compounds based on the action of LsrK kinase...
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Biological bypass shows promise in coronary artery disease
A new gene therapy that targets the heart and requires only one treatment session has been found safe for patients with coronary artery disease...
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Benzodiazepines increase stroke risk in Alzheimer’s patients
The use of benzodiazepines and benzodiazepine-like drugs was associated with a 20% increased risk of stroke among persons with Alzheimer’s disease, shows a recent study from the University of Eastern Finland.
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Non-invasive screening method shows properties of pills
Information on significant properties of pharmaceutical tablets, such as their mechanical strength and dissolution, can now be obtained without resorting to the conventional, time-consuming and destructive testing methods, according to a new study completed at the University of Eastern Finland.
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Brain diseases manifest in the retina of the eye
5 October 2016 | By Niamh Louise Marriott, Digital Content Producer
Dr Henri Leinonen investigated functional abnormalities of the retina using mouse models of human central nervous system diseases...