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Deletions in SARS-CoV-2 Spike protein drive antibody escape, study shows
Researchers have found that SARS-CoV-2 evades immune responses by deleting parts of its genetic sequence that encode for the Spike protein.
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University of Pittsburgh
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New CRISPR system edits body’s response to prevent immunity against AAVs
A novel CRISPR system that suppresses genes related to adeno-associated virus (AAV) antibody production has been developed to prevent immunity against the gene therapy.
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ZT-1a compound could be an alternative to surgery for brain swelling
Rodent models of stroke and hydrocephalus treated with ZT-1a had reduced brain swelling, according to scientists.
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Identifying the right mouse model for Huntington’s disease drug development
Scientists have evaluated mouse models used for developing treatments for mood disorders associated with Huntington's disease and have recommended which have greater potential for success.
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Mechanism identified of impaired dendritic cell function that weakens response to cancer
New research explains how accumulation of chemically modified lipids interferes with the function of a protein involved in the antitumor function of dendritic cells...