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Promising development of new drug to treat Alzheimer’s disease
In lab and fruit fly studies, the new peptide inhibitor effectively acted on both major aggregation-promoting hotspots of Tau proteins.
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Southampton University
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New insight into the key properties of an antibody needed to fight cancer
The findings have enabled researchers to design antibodies to activate important receptors on immune cells and deliver more powerful anti-cancer effects.
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Inhibiting PIP4K enzymes could help immune system fight cancer
Researchers identified a potential therapeutic involving the inhibition of PIP4K enzymes which could enable the immune system to destroy tumour cells.
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Spikes from AstraZeneca COVID-19 vaccine resemble SARS-CoV-2 S proteins
Using cryo-electron microscopy, researchers have shown that the Spike (S) protein on cells exposed to the AstraZeneca vaccine is highly similar to the SARS-CoV-2 S protein.
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Gold nanoparticles designed to seek out and isolate human bone stem cells
A team has designed gold nanoparticles to reveal specific bone stem cells, which could lead to treatments for major bone fractures.
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T-cell exhaustion may limit long-term immunity in COVID-19 patients
Researchers suggest patients who develop mild COVID-19 may not be able to fight reinfection very effectively because their CD8+ T cells show signs of exhaustion.
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Mass spec used to reveal glycan structures of COVID-19 Spike protein
High-resolution mass spectrometry has been used by researchers to map the glycan-processing states of the Spike protein of the SARS-CoV-2 virus, which causes COVID-19.
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Researchers find drug improves cancer immunotherapy in mice
A study has shown that in mice, the GKT137831 drug makes tumours more sensitive to immunotherapy, so could be used to improve cancer treatments.
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Stain-less laser-based imaging used for regenerative medicine research
Researchers create images from stem cells as part of an investigation into new optical techniques to monitor the cells' development...
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Research reveals antibody treatment pathway for severe allergic asthma
Blocking the action of two pro-inflammatory molecules can significantly reduce the symptoms of allergic asthma...
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New molecules could help in the fight to prevent cystic fibrosis
9 June 2016 | By Victoria White, Digital Content Producer
Researchers have identified new molecules that could help in the fight to prevent diseases caused by faulty ion channels, such as cystic fibrosis...
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A drug that heals broken bones faster and better
23 November 2015 | By Victoria White
Using bone samples from people undergoing hip replacement surgery, researchers were able to show that a drug that activates the Wnt pathway causes stem cells found within bones to divide and to turn into more bone cells...
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Possible solution for Alzheimer’s immunotherapy side effect
6 November 2015 | By Victoria White
Scientists have discovered that small changes in anti-amyloid antibodies preserves the immunotherapeutic activity without the inflammatory side effects...
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Scientists investigate the function of protein MHC1
6 November 2015 | By Victoria White
The scientists have been awarded £700,000 to work in collaboration with Unilever scientists to explore ways to minimise allergic reactions to additives in healthcare products...
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Scientists discover exercise mimicking molecule ‘compound 14’
28 July 2015 | By Victoria White
Scientists have developed a molecule, called 'compound 14', that acts as an exercise mimic, which could potentially help treat type 2 diabetes and obesity...