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Developing novel genome editing tools
In this Q&A, Dr Stephen Jones from Vilnius University Life Sciences Center discusses his work on the recent developments in genome editing tools at the university.
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Texas University
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A safer method for gene editing
Researchers at the University of Texas have redesigned a key component of a CRISPR-based gene-editing tool.
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IAIPs shown to reduce ischemic stroke damage in pre-clinical study
Inter-alpha inhibitor proteins (IAIP) demonstrated efficiency in reducing damage from an ischemic stroke, reveals pre-clinical study.
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Revealed protein structure could aid in Huntington’s disease treatment development
Using NMR spectroscopy, researchers have partially observed the structure of heat shock proteins that bind to proteins that cause Huntington's disease.
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New drug target for non-small cell lung cancer identified
A new study has suggested that the enzyme GFPT2 could be a useful target for non-small cell lung cancer (NSCLC).
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The Editors’ views: Drug Target Review’s 2020 round-up
The Junior Editors of Drug Target Review, Victoria Rees and Hannah Balfour, discuss some of the most noteworthy news and announcements from this year.
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LY6E identified as potential immunoprotein against SARS-CoV-2
A study has demonstrated that the LY6E protein inhibits SARS-CoV-2 infection in human cell cultures, so a drug mimicking it could be a therapy for COVID-19.
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Antiviral treatments lead to development of a new kind of cancer drug
Drugs that were being developed to treat enterovirus have also been found to treat certain cancers in mice.
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Early treatment could reverse autistic behaviour in tuberous sclerosis
Scientists may have found a sensitive time period where autism related social deficits could be reversed in tuberous sclerosis...
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Chemical oscillators offer a new level of molecular control
Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit computation within molecular systems...
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New insights reported on the function of BRCA1 in breast cancer
7 March 2016 | By Victoria White
Scientists have provided a deeper insight into how BRCA1 functions in normal breast tissue and how its loss results in breast cancer...
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Tc24 protein could hold the key to fighting Chagas disease
9 December 2015 | By Victoria White
Researchers have identified the molecule, Tc24, that is expressed by Trypanosoma cruzi and may facilitate the parasite's evasion of the host's immune system...
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Scientists engineer potential treatment for pertussis
3 December 2015 | By Victoria White
Preclinical testing demonstrated that the new antibodies work as a prophylaxis to provide short-term immunity and as a treatment to accelerate recovery...
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New drug protects against the effects of nuclear radiation
24 August 2015 | By Victoria White
A research team led by The University of Texas Medical Branch have reported a new breakthrough in countering the deadly effects of radiation exposure...
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Calcineurin inhibitor-based medications may protect against Alzheimer’s disease
9 June 2015 | By Victoria White
A new study has revealed that calcineurin inhibitor-based medications, such as Tacrolimus or cyclosporine, may also protect against Alzheimer’s disease...