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Novel method could determine which lymphoma patients will respond to CAR T-cell therapy
A new high-throughput approach has shown how patients whose tumours express CD58 are more likely to respond to CAR T-cell therapy.
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University of Texas MD Anderson Cancer Center
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Researchers discover new compounds to potentially combat leukaemia
Researchers from the US have identified several new small molecules that can induce mitophagy in leukaemia cells.
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Ultrasound-guided microbubbles boost immunotherapy efficacy
Researchers have developed an immunotherapy platform to improve both antitumor immune responses and responses to checkpoint inhibitors
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Natural killer cells and bispecific antibody target lymphoma tumours
In pre-clinical studies, researchers showed that cord blood-derived natural killer cells and a bispecific antibody eliminated lymphoma cells.
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Single-cell map of lung cancer sheds light on tumour development
A spatial atlas of early-stage lung cancer has been compiled at single-cell resolution, revealing new therapeutic targets.
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Novel inhibitor kills brain cancer cells missing ENO1 in mice, study shows
In pre-clinical studies, researchers have shown that a new therapy called POMHEX can destroy brain cancer cells that were missing one of two genes encoding the enolase enzyme.
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Drug candidate stops tumour growth with little toxicity in mice
A star-shaped molecule along with a modified platinum drug have demonstrated success at combatting tumours with few toxic effects in mice.
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Researchers identify pancreatic cancer protein drug target
A protein that causes pancreatic ductal adenocarcinoma has been identified as a therapeutic target by researchers.
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Immunotherapy and DNA damage repair combo could target lung cancer
Combination therapy with a CHK1 or PARP inhibitor, with an immune checkpoint inhibitor caused the regression of small cell lung cancer in all mice treated...