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Mesenchymal stem cells could be the key to bone regeneration

11 October 2021 | By Anna Begley (Drug Target Review)

Scientists have identified a subpopulation of mesenchymal stem cells with enhanced bone fracture healing and differentiation abilities.

news

The fate of cancer is all down to particular proteins

11 February 2020 | By Mandy Parrett (Drug Target Review)

Scientists in Japan have identified an important protein that can impact the course of cancer and its fate in the human body.

news

OX40-expressing follicular helper T cells can control rheumatoid arthritis

1 August 2019 | By Rachael Harper (Drug Target Review)

New study shows that a subset of follicular helper T cells contributes to the hyposialylation of autoantibodies in rheumatoid arthritis.

Novel gene in red blood cells may help adult newts regenerate limbs

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Novel gene in red blood cells may help adult newts regenerate limbs

6 June 2018 | By Drug Target Review

Japan-US research collaboration has found that red blood cells that express a novel gene may contribute to adult newt limb regeneration.

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Novel molecular pathway in cancer offers potential therapeutic targets

24 April 2017 | By Niamh Marriott (Drug Target Review)

The gene MAFK is known to be induced by the TGF-β signalling pathway, which is involved in breast cancer development. Scientists reported that the MAFK protein, in turn, induced cancerous behaviours in cells by switching on the breast cancer-associated gene GPNMB. MAFK thus represents a link between TGF-β signalling and…

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Stem cell reprogramming factor shown to control key metabolic change

9 March 2017 | By University of Tsukuba

KL4 could improve efficiency in stem cell generation

news

Orexin as a potential drug for treating septic shock

9 February 2017 | By Niamh Marriott (Drug Target Review)

Recent findings by Japanese scientists may be a breakthrough in developing a silver bullet for the treatment of septic shock.

news

Charles River demonstrates CRISPR/Cas9 genome engineering expertise

2 December 2016 | By Charles Rivers Laboratories

Charles River Laboratories has launched a full, end-to-end service offering of CRISPR/Cas9 genome engineering technology...

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