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Targeting RAS to overcome FLT3 AML drug resistance

22 April 2024 | By Drug Target Review

It was discovered that targeting RAS proteins prevent cancer cells from using different signalling pathways to escape cell death.

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How gene regulatory networks maintain FLT3-ITD mutated AML

22 December 2023 | By Drug Target Review

Using shRNA screening enabled researchers to investigate the roles of individual specific factors in maintaining the network found in AML.

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Prozac could be repurposed to treat age-related macular degeneration

12 November 2021 | By Anna Begley (Drug Target Review)

Fluoxetine - best known as Prozac - protected the macula from inflammation and degeneration in mice and could become a future treatment.

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Computational method developed to map chromosome folding in 3D

27 May 2021 | By Victoria Rees (Drug Target Review)

Researchers created their new method to analyse chromosomes in 3D, revealing how misconfigurations play a role in cancer.

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Understanding of COVID-19 infections in children will aid treatment development, say researchers

20 March 2020 | By Victoria Rees (Drug Target Review)

A statement from scientists has highlighted that improving the understanding of COVID-19 infections in children will help researchers to develop better treatments.

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Halting the spread of brain cancer

26 November 2018 | By Drug Target Review

Mouse models used to show how convection enhanced delivery caused glioma cells to invade the rest of the brain could help to prevent this spread in future...

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GDF11 protein found to inactivate triple-negative breast cancer cells

21 November 2017 | By Dr Zara Kassam (Drug Target Review)

Researchers detail a possible way to re-engage a tumour suppressor protein, that has been found to be inactivated in triple-negative breast cancer cells...

news

Researchers find way to trigger red blood cells on demand

4 November 2015 | By Victoria White

The discovery could represent a significant step forward in the battle against anaemia...

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