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Vanderbilt University Medical Center (VUMC)

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Protective mutation found in kidney disease gene

17 October 2023 | By Drug Target Review

A new discovery about a different protective genetic mutation in apolipoprotein L1 could have major implications for kidney health.

news

SARS-CoV-2 mAb cocktail effective against all known variants of virus

8 March 2021 | By Victoria Rees (Drug Target Review)

A monoclonal antibody (mAb) cocktail, that targets sites on the Spike protein other than the E484K residue, can neutralise SARS-CoV-2.

news

Pre-clinical study supports remdesivir as COVID-19 treatment

13 July 2020 | By Hannah Balfour (Drug Target Review)

Scientists demonstrated that remdesivir can inhibit SARS-CoV-2 replication in human lung cells and improve lung function in mice with COVID-19.

long thin filament-like viral particle in brown with blue surface glycoproteins that look like polka dots

news

Experiments with Marburg virus reveal novel antibody protective mechanisms

22 April 2020 | By Hannah Balfour (Drug Target Review)

Researchers discovered the monoclonal antibodies of a convalescent Marburg infection patient bound to the glycoprotein and combatted infection in two novel ways.

coronavirus particle in white on a black background

news

EIDD-2801 shows efficacy against COVID-19 in human cells and mice

7 April 2020 | By Hannah Balfour (Drug Target Review)

Collaborators have shown that the broad spectrum oral antiviral EIDD-2801 could be a potential prophylactic or therapeutic for COVID-19 and other coronaviruses.

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Recommended

Vanderbilt University Medical Center (VUMC)

Protective mutation found in kidney disease gene

SARS-CoV-2 mAb cocktail effective against all known variants of virus

Pre-clinical study supports remdesivir as COVID-19 treatment

Experiments with Marburg virus reveal novel antibody protective mechanisms

EIDD-2801 shows efficacy against COVID-19 in human cells and mice