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New drug shows promise as immune therapy for cancers

17 October 2019 | By Rachael Harper (Drug Target Review)

A therapy has been developed which uses a synthetic RNA molecule developed to fight viruses to trigger an immune response against tumours in mice.

news

Researchers develop new immuno-oncology technique

15 October 2019 | By Victoria Rees (Drug Target Review)

A team has used viral gene editing and CRISPR to form a system that marks tumours for destruction, potentially improving immunotherapies.

news

Allergy-driving cells identified as potential drug targets

2 August 2019 | By Victoria Rees (Drug Target Review)

Researchers have discovered a subtype of immune cells that contribute to allergic reactions and anaphylaxis, providing a drug target.

news

BDNF–VEGF interplay key to rapid antidepressant actions

31 January 2019 | By Dr Zara Kassam (Drug Target Review)

A study reveals a complex interplay of two different growth factors in the rapid and long-lasting antidepressant effects of ketamine...

news

Nuclear tracers help assess new drugs for neurodegenerative diseases

21 January 2019 | By Dr Zara Kassam (Drug Target Review)

New nuclear medicine tracers could help medical researchers find a cure for Alzheimer's and other neurodegenerative diseases.

news

Malaria vaccine targets PMIF

13 July 2018 | By Drug Target Review

A new malaria vaccine targets the protein PMIF, which is crucial in the life cycle of malaria parasites...

news

PNA gene editing technique cures beta-thalassemia in utero

10 July 2018 | By Dr Zara Kassam (Drug Target Review)

Researchers have for the first time used a gene editing technique to successfully cure a genetic condition in a mouse model...

news

MS risk in children detected with MRI brain scans

16 October 2017 | By Nic Losardo (Drug Target Review)

MRIs can reveal changes in the brain associated with MS before the clinical symptoms of the disease appear in children...

news

Cytokine molecules unearth development of progressive MS

19 September 2017 | By Dr Zara Kassam (Drug Target Review)

Scientists have uncovered two closely related cytokines molecules involved in cell communication that explain why some people develop progressive MS...

news

Elimination of specific neurons outside the brain by new technique triggers obesity

3 April 2017 | By Niamh Marriott (Drug Target Review)

A research team from Instituto Gulbenkian de Ciencia (IGC, Portugal), developed a new genetic technique that allows the elimination of specific neurons of the peripheral nervous system without affecting the brain.

news

Study identifies how altered gut microbiota causes obesity

8 June 2016 | By Victoria White, Digital Content Producer

In a new study, a Yale-led team of researchers has identified how an altered gut microbiota causes obesity...

news

Combination therapy cures babesiosis in mice

6 June 2016 | By Victoria White, Digital Content Producer

Yale researchers have reported a novel combination therapy that cures an emerging infectious disease, babesiosis...

news

Pathogen busting bacteriophage found in a pond

26 May 2016 | By Victoria White, Digital Content Producer

A bacteriophage, found in a pond in Connecticut, attacks a common multi-drug resistant bacterial pathogen called Pseudomonas aeruginosa...

news

SGK1 identified as potential target to reverse effects of PTSD

28 October 2015 | By Victoria White

Experimentally reducing SGK1 activity in rats induced learned helplessness ( a behaviour thought to mimic one aspect of PTSD), while overexpressing the protein reduced it...

news

Technology for large-scale protein manufacture unveiled

11 September 2015 | By Victoria White

Researchers have developed the user-friendly technology to help scientists understand how proteins work and fix them when they are broken...

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