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Research into CDK8 oncogene could improve design of future therapeutics

A study has shown that type II kinase inhibitors targeting…

29 January 2020 | By Hannah Balfour (Drug Target Review)

A study has shown that type II kinase inhibitors targeting CDK8 alone are ineffective because mutations leave them inactive, suggesting future therapies should target CDK8 in complex.

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Dr Claus Kuhn

Research into CDK8 oncogene could improve design of future therapeutics