Ion channels: Small molecules versus biologics – the quest for the ideal Nav1.7 inhibitor
Ion channels modulate and control many fundamental physiological processes in…
Ion channels modulate and control many fundamental physiological processes in various tissues and alterations in their functions give rise to a wide range of pathophysiologies, which makes them important drug targets. Indeed, for decades, drugs modulating ion channel activity have been targeted by the pharmaceutical industry. Historically, however, developing drugs…