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Philip Rawlins (Group Leader at Domainex)

 

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Advancements in hit identification for membrane protein drug discovery

GPCRs are crucial drug targets, but their complex structures present…

7 April 2025 | By

GPCRs are crucial drug targets, but their complex structures present significant challenges in drug discovery. In this article, Domainex’s Philip Rawlins explores how fragment-based screening and innovative technologies like PoLiPa are helping to overcome these hurdles, with a focus on the Adenosine A2a receptor.