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Advanced techniques in toxicity testing

Tune in to this episode where we explore how innovative assays and human-relevant cell models are transforming toxicity screening in drug development.

In this episode titled ‘Advanced techniques in toxicity testing‘, we explore advanced toxicity testing methods.

This conversation features Professor Ruth Roberts, co-director and co-founder at ApconiX and Dr Oksana Sirenko, Senior Scientist at Molecular Devices.

Key learning points:

 

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  • What strategies can be employed to enhance the predictivity and reliability of toxicity assessments?
  • How does high-throughput screening contribute to accelerating drug discovery and development?
  • What role can emerging technologies, such as machine learning and AI, play in advancing toxicity testing methods?

This podcast is sponsored by Molecular Devices. With its innovative life science technology, Molecular Devices makes scientific breakthroughs possible for academic, pharmaceutical, government and biotech customers. Head to moleculardevices.com to find out more.

About the speakers

Professor Ruth Roberts, co-director and co-founder at ApconiX

Ruth Roberts

A director and co-founder of ApconiX, Professor Ruth Roberts has over 25 years of experience in leading drug safety. Ruth is also Chair and Director of Drug Discovery at the University of Birmingham, UK and previously Global Head of Regulatory Safety at AstraZeneca.

 

Dr Oksana Sirenko, Senior Scientist at Molecular Devices

Oksana SirenkoDr Oksana Sirenko is the senior manager of assay development at Molecular Devices, working on the development of complex cell-based models for 3D biology, as well as high-content imaging and assay automation.

After developing high-throughput cell-based assays at several biotechnology companies, such as Bayer, Fibrogen, and Bioseek, she became part of the Molecular Devices team as a research scientist in 2009. She is responsible for developing and optimising stem cell-derived 3D models for anti-cancer drug screening, as well as drug toxicity assessment for neurons, the cardiovascular system, and the liver.

Oksana holds a PhD in Biochemistry/Biophysics, has over 15 years of industry experience, and has authored over 35 scientific papers.

 

 

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