How mRNA technology could revolutionise therapeutics
Posted: 29 July 2024 | Drug Target Review | No comments yet
In this episode, we explore how mRNA technology could revolutionise cancer therapeutics.
In this podcast episode, titled ‘How mRNA could revolutionise therapeutics’, we will be discussing how mRNA vaccines for cancer treatment engage with the immune system to illicit an anti-tumour response, how they could synergise with other cancer treatments, as well as which cancers show most promise for this approach.
This conversation features Dr Rebecca Boohaker, Director of Oncology at Southern Research, and Fusataka Koide, Senior Director of Business Development at Southern Research.
Key discussion points:
- The specific challenges researchers face in utilising mRNA technology for cancer treatment
- How mRNA vaccines for cancer differ from conventional cancer treatments, and the advantages they offer
- The strategies being explored to enhance the delivery and stability of mRNA vaccines tailored for cancer immunotherapy
- The current advancements in mRNA vaccine development
This podcast is in association with Molecular Devices. With its innovative life science technology, Molecular Devices makes scientific breakthroughs possible for academic, pharmaceutical, government and biotech customers. Head to moleculardevices.com to find out more.
About the speakers
Dr Rebecca Boohaker, Director of Oncology at Southern Research
Boohaker is the study director for the oncology department. She designs, oversees, executes and interprets all cancer-related in vivo studies to evaluate potential cancer treatments, including cancer-fighting viruses and other agents that might help combat the disease. Trained primarily as a molecular biologist, Boohaker’s graduate work at the University of Central Florida resulted in a targeted peptide therapy to combat triple negative breast cancer. Since joining Southern Research, her recent work has focused on chemo-resistant colorectal cancers, as well as pancreatic cancers, which are aggressive and highly resistant to treatment. Boohaker received a bachelor’s degree in biology from the University of Alabama at Birmingham and a doctorate in biomedical sciences from the University of Central Florida. Her postdoctoral work at Southern Research focused on cancer biology and DNA damage repair.
Fusataka Koide, Senior Director of Business Development at Southern Research
Koide joined Southern Research’s infectious disease program in 2007. He has 18 years of experience in research and programme leadership, and he specialises in animal studies to evaluate novel vaccines and therapeutics for emerging infectious diseases including dengue, Zika, and yellow fever. In his previous experience, he worked at Nabi Pharmaceuticals, where he was involved in the research and development of a vaccine for Methicillin-resistant Staphylococcus aureus (MRSA). He previously worked Memorial Sloan-Kettering Cancer Center, where he worked on studies related to newly developed cancer vaccines and also was involved in more than 10 phase I and phase II clinical trials. He is currently directing multiple dengue and Zika vaccine pre-clinical and clinical programmes for commercial and government clients. His most recent research interests focus on the animal model development for Zika virus infection. Koide received his master’s degree in immunology and microbiology at the New York Medical College.
Related topics
Chemotherapy, Oncology, RNAs, Targets, Technology, Therapeutics, Vaccine, Vaccine development
Related conditions
Cancer
Related organisations
Southern Research