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Analysis
Mucin 6 gene indicates predisposition to late-onset Alzheimer’s
Scientists have idenified that variation in a gene called Mucin 6 appears to indicate a tendency for acquiring Alzheimer’s disease.
Computational model identifies new candidate cancer genes
A novel computational method has led to the discovery of genes whose alteration may contribute to cancer susceptibility and may lead to new therapeutic targets for cancers.
Application note: Cell Lysate Sample Handling with Simoa Bead-Based Assays
Cell lysates can be prepared using a variety of methods including physical disruption, reagent-based lysis, or a combination.
eBook – Getting the Inside Story: In Vivo Imaging
In vivo imaging has been an indispensable and powerful tool in biomedical research, enabling a number of significant breakthrough discoveries.
Application note: Analysis of Inflammatory Plasma Biomarkers in Cancer Patient Samples
The Simoa CorPlex Human Cytokine Panel 1 is a multiplex immunoassay for the quantitative measurement of 10 inflammatory biomarkers in serum and EDTA plasma.
Mitocans partner up to provide powerful leukaemia treatment
A pioneering team of scientists from Rice University has discovered that a particular combination of chemotherapeutics, including mitocans that target mitochondria, form a powerful treatment for acute myeloid leukaemia patients.
New antiviral drug demonstrated to effectively treat influenza in models
A new antiviral drug has been reported in a study that researchers believe has high clinical potential as a next-generation influenza drug.
New gene editing tool could correct 89 percent of genetic defects
'Prime editing', a new CRISPR genome-editing approach, is capable of directly editing human cells in an accurate and efficient way.
New horizons in small molecule solubility screening
22 October 2019 | By Halo Labs
Aqueous solubility of small molecule compounds is an essential parameter during the hit-to-lead stage of drug discovery as well as lead optimization and formulation. Low solubility can result in misleading ADMET/DMPK analyses if some fraction of a compound precipitates. Watch on-demand to find out more!
LVNC congenital heart condition linked to faulty signalling pathway
A new study, which has shown that the congenital heart condition LVNC could be be caused by signalling defects, may lead to potential therapies.
Cancer-suppressing cells identified in pancreatic cancer
Cells containing Meflin play a role in restraining the progression of pancreatic cancer and could lead to new therapies against the disease.
Bacterial strain identified that determines fate for rotavirus sufferers
Scientists in the US have identified a particular bacterial strain, Segmented filamentous bacteria (SFB), that can prevent and cure rotavirus in mice.
Video: SpectraMax i3x Multi-Mode Microplate Reader
An unlimited breadth of user-upgradeable application modules expands your research capabilities and evolves with your research
Possible target found for idiopathic pulmonary fibrosis treatment
A new study shows that using therapeutic antibodies to block the interleukin-11 protein can reverse idiopathic pulmonary fibrosis.