news
Cyclisation reaction enables screening of macrocyclic compounds libraries
Libraries of more than 9,000 macrocyclic molecules below 1 KDa have been generated, small enough to cross cell membranes and reach targets.
List view / Grid view
Analysis
news
Osteoporosis in mice reversed with new drug target
A pharmaceutical target has been identified by Duke University that, when activated, can reverse bone degradation caused by osteoporosis.
news
New drug target for glioblastoma identified by study
A new drug target for treating glioblastoma has been identified from a cellular pathway found to contribute to the spread of glioma stem cells.
news
New study reveals causes of stem cell transplant rejection
A new study has shown that mutations in mitochondrial DNA induced by cell reprogramming may trigger an immune response.
news
Optofluidic chip platform developed for single molecule analysis
A new platform has enabled an unprecedented level of control over individual molecules and particles on a chip for high-throughput analysis.
news
Genes responsible for gender differences in tumours identified
A new study has identified possible regulators that determine differences in cancer tumours between genders.
news
Genes linked to Alzheimer’s risk have been identified
Two genes that influence risk Alzheimer's disease could provide scientists with new targets for delaying the onset of the condition's symptoms.
news
Blood-brain barrier role in Alzheimer’s patients revealed by tissue model
A new study has found that damage caused by Alzheimer's allows toxins to enter the brain, further harming neurons.
news
Therapeutic target for Kennedy’s disease and prostate cancer proposed
A chaperone protein has been identified as a possible therapeutic target for the treatment of Kennedy's disease and prostate cancer.
news
Potential treatment target identified for Crohn’s disease
Researchers have identified a pathway in the immune system activated in Crohn's disease which could lead to investigating new treatments.
news
New drug could be used for targeted cancer therapies
A new drug called IP1867B, which could be used for future treatments of brain tumours, is being examined.
news
New model predicts cognitive decline two years ahead
Researchers hope the system can choose the right patients to enroll in clinical trials, to speed discovery of drug treatments.
news
Experimental treatment slows prion disease
A new experiment has not only slowed the progression of the prion disease, scrapie, it also extended the lives of prion-infected mice
news
OX40-expressing follicular helper T cells can control rheumatoid arthritis
New study shows that a subset of follicular helper T cells contributes to the hyposialylation of autoantibodies in rheumatoid arthritis.