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3D image of insulin and its receptor revealed
After combining over 700,000 2D images, researchers have finally been able to build a 3D image of how insulin binds to its receptor...
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Protein adhesion complex cell structure identified
A cell structure identified has given an insight into how cells attach to their surroundings, and could be used to discover potential actions of new drugs...
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Single molecule fluorosequencing to transform biological research
Single molecule fluorosequencing could revolutionise the way researchers analyse disease, with the method enabling the investigation of single cells...
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AI algorithm accurately predicts Alzheimer’s disease onset
Scientists have developed an algorithm that can more accurately predict cognitive decline that leads to Alzheimer’s disease. Early preventive measures may help delay and even halt the disease’s onset.
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Application note: Increasing throughput with dual emission AlphaLISA-AlphaPlex assay and simultaneous dual emission detection
Multiplexing AlphaLISA type assays will increase throughput while sample expenditure and costs are minimised. The ability of the PHERAstar FS microplate reader to perform simultaneous dual emission detection of this assay will allow users to double the information obtained from each well in the same amount of time as needed…
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Kidney disease biomarker could help detect COPD
A biomarker usually used with kidney disease, could potentially be used to detect COPD through identifying levels of albuminuria in urine...
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A universal flu vaccine may be in sight
Researchers from Oxford have identified the initial steps on the path towards creating a universal influenza vaccine that could last for life...
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Np63a should be targeted in squamous cell carcinomas
A team of researchers have identified that to target p63, both TGFB2 and RHOA tumour suppressor genes should be activated...
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Enhanced 3D neuron imaging could diagnose brain disease
Researchers have combined an open source software programme and commercially available hardware to image neuron activity at high resolution...
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Transparent high-resolution EEG array allows brain imaging
Researchers have developed a see-through, dual-layered, mesh EEG device which is capable of measuring the electrical activity of individual neurons...
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Expert view: GMP proteins for therapeutic manufacturing: combining consistency, safety, and supply
Cell therapies offer revolutionary new approaches for treating humandisease. Most of these treatments use GMP cytokines and growthfactors for the differentiation, expansion, and maintenance of cells.It is critical that GMP protein suppliers offer the optimal combinationof consistency, safety, and stable supply chain.
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Complex biology for the precision medicine era: re-thinking the drug discovery process
Complex biology is a discipline acknowledging that performing biological experiments in vitro should take account of the complexity of the biological context.1 While this may be a noble aim, it has proven difficult to incorporate these elements into the drug discovery process, especially at the high-throughput screening (HTS) stage.2
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Computational analysis identifies a new clinical phenotype of severe malaria
Researchers have applied a computational analysis based on networks in order to identify biologically relevant phenotypes apart from those currently defined by the WHO...
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Venoms could be used to treat cancer and autoimmune diseases
Venoms are continually being researched as potential chemicals for medicinal therapeutics to treat autoimmune diseases and diabetes...
