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Info kit: Metabolomics in pharmaceutical research
Accelerate the discovery process of new drugs and targets with a better understanding of the metabolome and lipidome during drug development.
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Analytical Techniques
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Application note: High-content phenotypic profiling using the cell painting assay
The cell painting assay uses up to six fluorescent dyes to label and visualize a variety of subcellular structures at the single cell level.
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Molecular insights into LSCC may lead to new drug targets
New insights into lung squamous cell carcinoma (LSCC) have emerged from a proteogenomic study, leading to the identification of potential drug targets.
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Novel database could accelerate drug repurposing for various diseases
NICEdrug.ch is an open-access database that may help scientists assess potential drugs for a range of diseases more quickly.
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Genes behind antibiotic activity in bacteria uncovered by metabologenomics
Researchers have used comparative metabologenomics to uncover what may be “silencing” bacteria to produce desirable compounds.
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ebook: High-Throughput Data Management in process development
Cell Line Development and cell culture process teams, are you geared up to leverage the vast amount of data generated by high-throughput?
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High-quality, rapid technique developed for imaging in vivo
A US team has designed a high-quality, high-speed imaging system that could lead to new understandings of complex tissue specimens.
webinar
Scalable solutions for automated sample preparation in label-free compound profiling
14 July 2021 | By Analytik Jena
In this on-demand webinar, based on field experiences with our research partners, Analytik Jena provides an overview of application demands for a reliable sample preparation automation – from a small and easy-to-use workstation, to a fully automated integration solution by Analytik Jena.
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Application note: High-throughput IgG quantitation platform for clone screening during drug discovery and development
Every manufacturing process for potential biologics begins with cell line development, whether it’s for clinical trials or a market launch.
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Whitepaper: Buying a digital informatics system for your R&D?
Examining existing R&D processes with a consolidated approach enables the stop of disjointed workflows to engage on the digitisation journey.
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ebook: Optimise your high value cell lines
As interest in biotherapeutic proteins grows, the need to reduce cell line development costs and the time to market is more critical than ever.
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Product hub: Octet® R series systems
Discover the new Octet R series systems, a comprehensive solution for screening and characterising molecular interactions such as protein-protein or protein-drug interactions.
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The use of biophysical methods in the hit-to-lead process
Optimisation of a hit towards a lead happens in a variety of ways, as a lead needs to meet various criteria such as activity, affinity to the target, selectivity, solubility, permeability or metabolic stability to become a promising candidate. A balance between in vitro profiles and pharmacokinetic attributes has to…
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Researchers visualise metabolic processes at the single-cell level
Scientists have used imaging methods and machine learning to understand cellular metabolism at the single-cell level.
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ebook: Why you need to digitally transform your R&D organisation
Despite many companies considering digital transformation a top priority, research shows that 70% of digital transformation initiatives fail. In this ebook, we explore why and how the right approach can see your organisation succeed.