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Animal Models

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New organoid emulates development of the human heart

7 April 2023 | By Ria Kakkad (Drug Target Review)

The team are the first researchers in the world to successfully create an organoid containing both heart muscle cells and cells of the outer layer of the heart wall.

Autism. Autism spectrum disorder(ASD). Autism word made out of playdough. Wooden background. Close up.

news

Researchers find ancient virus genome drives autism

14 March 2023 | By Ria Kakkad (Drug Target Review)

The scientists revealed in mice models that endogenous retrovirus activation increases a foetus’s susceptibility to autism.

news

Usher syndrome: first nonhuman primate model

14 February 2023 | By Izzy Wood (Drug Target Review)

US researchers evaluate an experimental gene therapy in the first ever nonhuman primate model for Usher Syndrome.

Small crying girl child feel scared of injection in hospital. Nurse or doctor hands with syringe, little kid afraid of vaccination. Healthcare and medicine concept. Flat vector illustration.

news

A promising oral drug delivery platform could replace injections with pills

6 January 2023 | By Ria Kakkad (Drug Target Review)

The researchers explored the possibility of using the probiotic bacteria Lactobacillus reuteri as a novel oral drug delivery platform to treat rheumatoid arthritis in an animal model.

Non-alcoholic fatty liver disease NAFLD the doctor is holding a sign.

news

Scientists investigate the multi-omic landscape of NAFLD-to-NASH progression

15 December 2022 | By Ria Kakkad (Drug Target Review)

Researchers have presented comprehensive multi-omic profiles to identify genes, non-coding RNAs, proteins, and plasma metabolites involved in NAFLD-to-NASH progression.

Salivary gland in human mouth. Parotid, submandibular, and sublingual glands. Produce of saliva through a system of ducts. Xerostomia oral disease anatomical poster. Medical 3d vector illustration.

news

P53 could be key to therapies for salivary gland cancer

9 December 2022 | By Ria Kakkad (Drug Target Review)

Mouse models show that activating a non-mutated form of the gene could lead to developing therapies for salivary gland cancer.

article

Five recent CRISPR drug target discoveries

21 November 2022 | By Izzy Wood (Drug Target Review)

This article highlights five of the latest findings revealed using CRISPR that could be used in the development or design of new therapies.

news

Is the Nile rat the new animal model for diabetes research?

14 November 2022 | By Izzy Wood (Drug Target Review)

US researchers, using genome sequencing, put forward the Nile rat as the new model organism for diabetes research.

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Animal Models