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Weapon bacteria could be copied to create new forms of antibiotics
New antibiotics could be designed by discovering the mechanism a weapon bacteria uses to vanquish their competitors.
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Antibiotics
Antibiotics are a type of antimicrobial drug used in the treatment and prevention of bacterial infections.
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High-throughput screening used to discover new class of antibiotics
Researchers have used a high-throughput screening method to test over 125,000 molecules and identify a new class of antibiotics.
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Expert view: Advancing antibody discovery with picodroplet technology
It is predicted that there will be 70 new monoclonal antibody (mAb) biotherapeutics available by 2020.
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Potential sepsis prevention in burn patients found with novel approach
A new study has demonstrated the possibility of treating antibiotic-resistant Pseudomonas aeruginosa which causes sepsis in burn patients.
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How bacteria behind hospital infections block out antibiotics revealed
Scientists have shown that drug-resistant bacteria infections shut out antibiotics by closing tiny doors in their cell walls.
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Anti-viral immune discovery could lead to improved vaccines
A molecular switch that impacts immune responses to viral infections has been identified which could lead to better strategies to develop vaccines.
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Synthetic molecules could provide new antibiotics
Using a novel technique, researchers have created new molecules effective at killing bacteria, providing new antibiotic drug targets.
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Novel technique reveals how TB antibiotics reach their targets
Researchers have used a new method to understand how antibiotics fight TB, which can guide future drug developments.
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Application note: Detection of anti-drug antibody (ADA) using single molecule counting (SMCTM) technology
All biological therapeutics have the potential to induce an immunemediated response ranging from benign to severe adverse effects.
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Gut microbiome directs immune system to fight cancer
The advent of immune checkpoint inhibitors is a major breakthrough in cancer immunotherapy...
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Book mechanism identified as communication method for bacterial toxins
Researchers have identified the mechanism by which highly toxic compounds communicate, and how they use vesicles to be transported...
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Simple mechanism that ensures bacterial resistance
The team used techniques used by physicists along with highly specialised equipment to investigate deep into the bacterial membrane...
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Peptide research gives insight on tackling bacteria
Researchers have paved the path towards redesigning antibiotics through the alteration of the peptide assembly involved in the process...
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Naturally occurring potent antibiotic revealed
A natural antibiotic was found to be made from an enzyme, through it triggering chemical reactions that help the production of the bacterial toxin...
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CRISPR repurposed to develop better antibiotics
Mobile-CRISPRi could be used to guide gene expression, in turn control levels of proteins produced, enabling scientists to identify key antibiotic targets...
