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Antibodies

computer image of a dark grey ball of cells, a 'tumour', covered in blood vessels withing pink tissue

news

Novel antibody slows cancer growth and metastasis in mice

27 April 2020 | By Hannah Balfour (Drug Target Review)

The antibody targets a cell receptor in blood vessels and slowed breast and lung cancer growth as well as metastasis in murine models.

news

New malaria vaccine candidate shows promise in non-human primates

24 April 2020 | By Victoria Rees (Drug Target Review)

Using an antibody to a particular malaria protein called PfGARP, researchers have developed a new strategy for designing a malaria vaccine.

white blob representing a Natural Killer T cell attaching an orange cancer cell on a red tissue-like background

article

Developing immunotherapies for hard-to-treat cancers

23 April 2020 | By Hannah Balfour (Drug Target Review)

Exploring how therapies with multi-faceted approaches could improve options for treatment-refractory cancers, like pancreatic and triple-negative breast cancer.

long thin filament-like viral particle in brown with blue surface glycoproteins that look like polka dots

news

Experiments with Marburg virus reveal novel antibody protective mechanisms

22 April 2020 | By Hannah Balfour (Drug Target Review)

Researchers discovered the monoclonal antibodies of a convalescent Marburg infection patient bound to the glycoprotein and combatted infection in two novel ways.

news

Novel antibody treatment for OCD demonstrates efficacy in mice

22 April 2020 | By Victoria Rees (Drug Target Review)

Researchers who administered an antibody to neutralise an OCD-associated protein in mice found it reduced their anxious behaviours.

news

UK government funds 21 new research projects into COVID-19

20 April 2020 | By Victoria Rees (Drug Target Review)

A total of 21 COVID-19 research projects have been granted funding by the UK government, including vaccine and therapeutic development.

article

High-throughput screening for antibody-based drugs

16 April 2020 | By Victoria Rees (Drug Target Review)

A collaboration between academia and industry has produced an assay and new screening technique which utilises directed evolution for the discovery of antibody-based drugs.

news

Celltrion selects 14 lead monoclonal antibodies for COVID-19 treatment

16 April 2020 | By Victoria Rees (Drug Target Review)

After screening 300 antibodies, Celltrion has identified the 14 most powerful that could potentially combat the COVID-19 coronavirus.

article

COVID-19 and big pharma: what are 15 leading companies doing to develop a coronavirus vaccine?

9 April 2020 | By Victoria Rees (Drug Target Review)

A new report has revealed the vaccine R&D efforts of 15 of the leading pharmaceutical companies to combat the COVID-19 coronavirus.

video

Video: Increased reproducibility with KingFisher™ instruments

8 April 2020 | By Thermo Fisher Scientific

ESHG 2019 Conference Presentation: Using KingFisher™ to increase reproducibility in new applications using challenging samples.

news

Researchers reveal how SARS antibody binds to COVID-19 coronavirus

7 April 2020 | By Victoria Rees (Drug Target Review)

The interaction between a SARS antibody called CR3022 and the COVID-19 coronavirus has been mapped by researchers, revealing a viral vulnerability.

news

Celltrion to select lead antibody candidates to fight COVID-19

6 April 2020 | By Victoria Rees (Drug Target Review)

Following the screening of antibodies, Celltrion will now identify the most potent out of 300 hits that work against the COVID-19 coronavirus best.

news

Collaboration to develop inhaled mRNA-based antibody therapy for COVID-19

6 April 2020 | By Hannah Balfour (Drug Target Review)

Two companies, Neurimmune and Ethris, will leverage their technologies to research, develop and produce an inhaled therapy for COVID-19.

news

Novel COVID-19 vaccine shows efficacy in mice

3 April 2020 | By Victoria Rees (Drug Target Review)

Researchers have developed a vaccine against the COVID-19 coronavirus which induced the rapid production of antibodies in mice.

bags of yellow-coloured blood plasma labelled for use as therapeutics

news

FDA and BARDA to collaborate with Grifols on COVID-19 therapeutics

30 March 2020 | By Hannah Balfour (Drug Target Review)

Grifols will leverage their resources to develop and test convalescent plasma-derived COVID-19 therapeutics in partnership with the FDA and BARDA.

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Antibodies