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Experimental HIV vaccine induces bnAb production in models
Researchers have developed a vaccine for HIV that has shown success in rabbits, by neutralising a wide range of HIV strains using bnAbs.
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Antibodies
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Better HIV, lupus and hep C treatments possible with malaria discovery
A new discovery on how the immune system responds to malaria infection could lead to better treatments for hepatitis C, HIV and lupus.
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Researchers identify antibody that could treat pulmonary arterial hypertension
A study has revealed a new antibody that reverses the effects of pulmonary arterial hypertension in rodents and cell models.
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A faster and stronger rabies vaccine has been developed
A new rabies vaccine strategy enhanced the speed and magnitude of the anti-rabies antibody responses and could improve the efficacy of currently used vaccines.
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New vaccine protects from widespread, costly infection
A new vaccine against the Staphylococcus aureus infection has proven effective in experiments with mice, with an 80 percent survival rate.
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New HIV vaccine candidate design developed by researchers
A study has demonstrated a novel vaccine design in mice which could be used to immunise patients against HIV.
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Protective antibody discovery could lead to better flu treatments
Researchers have identified a set of three antibodies that they suggest could become the basis for a new antiviral treatment and inform the development of new influenza vaccines.
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Reasons why targeted immuno-oncology drugs sometimes fail discovered
A new study has shown the specific cellular mechanisms that limit the ability of CD8 T cells to infiltrate the tumour microenvironment, which could guide new immunotherapeutic strategies in cancer.
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Antibodies used to treat and reverse MS symptoms in mice
Researchers have identified a protein on the surface of cells that cause MS and have used antibodies as an effective treatment for the condition in mice.
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Nipah and Hendra virus attack neutralised by potent antibody
Researchers have shown that a monoclonal antibody prevents viruses from fusing with cell membranes to gain entry.
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Possible target found for idiopathic pulmonary fibrosis treatment
A new study shows that using therapeutic antibodies to block the interleukin-11 protein can reverse idiopathic pulmonary fibrosis.
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New vaccine prevents genital herpes in mice and guinea pigs
Almost all animal subjects exposed to genital herpes were protected by the novel vaccine.
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Therapeutic antibodies in cancer therapy
Monoclonal antibodies have shown great promise in the treatment of various cancers. This article discusses how therapeutic antibodies are produced and the various treatment strategies that are currently being adopted.
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Designing proteins from scratch with computer science
Marc Baiget-Francesch highlights interesting developments in the field of protein drug design and explains how continual software improvements are speeding up the process.
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Transplanted brain stem cells survive without anti-rejection drugs in mice
An experiment with mice has successively blocked the immune system's T cells from killing transplanted cells.