Antibodies

Enzo Life Sciences

Promising drug developed for ovarian and pancreatic cancers

22 July 2019 | By Drug Target Review

An antibody has been developed to block a protein secreted by the cells surrounding ovarian and pancreatic cancer tumours.

Whitepaper: IHC/ICC Protocol Guide

22 July 2019 | By Bio-Techne

Immunohistochemistry (IHC) and immunocytochemistry (ICC) are techniques employed to localize antigen expression and are dependent on specific epitope-antibody interactions.

Whitepaper: Neural Cell Culturing Guide

22 July 2019 | By Bio-Techne

The advent of in vitro culturing of neural cells has been central to driving our understanding of the nervous system.

Whitepaper: Immune Cell Isolation & Culture

22 July 2019 | By Bio-Techne

Immune cell isolation and culture are necessary for both basic research aimed at investigating the functions of different immune cell types, and for expanding specific immune cell populations for therapeutic purposes.

New potential liver cancer treatment found with biomarker-guided strategy

16 July 2019 | By European Pharmaceutical Review

A cellular pathway may reduce side effects and extend immunotherapy duration in patients with the most common form of liver cancer.

Role of protein in spread of cytomegalovirus discovered

11 July 2019 | By Victoria Rees (Drug Target Review)

A study has revealed the role of a protein which enables human cytomegalovirus to spread, the number one cause of congenital birth defects in the world.

Discovering new routes to cancer drug discovery with neutrons

8 July 2019 | By Matthew Blakeley

From the world’s flagship neutron science facility, Institut Laue-Langevin (ILL), Matthew Blakeley shares insights into how they are harnessing the power of neutrons to aid their search for new cancer treatments.

Scientists have discovered important redundancies in T cells

21 June 2019 | By Drug Target Review

Redundancies have been discovered in the biochemical signalling pathways of immune cells which could impact cancer immunotherapy.

Protective antibodies identified that could be key to malaria vaccine

18 June 2019 | By Drug Target Review

A new study has identified antibodies that may hold the key to creating the first effective vaccine against malaria infection in the blood.

Antibody treatment allows mismatched stem cell transplant in mice

18 June 2019 | By Drug Target Review

New study finds a combination of antibodies that can prepare mice to accept stem cells from an immunologically mismatched donor.

Image-based characterisation of cancer biotherapeutics

17 June 2019 | By Laura Murch, Siobhán Leonard, Victoria Juskaite

Scientists from LifeArc, an independent medical research charity in the UK, explain how they’re using the latest imaging technologies to progress drug discovery campaigns and identify the most promising candidates for antibody-based therapies.

Radiochemistry and drug synthesis ‘in a flash’

12 June 2019 | By Professor Dr Jason P. Holland - University of Zurich

Conventional methods for radiolabelling proteins are time consuming and difficult to automate. In this article, Jason P. Holland discusses how combining photochemistry with radiochemistry enables development of radiolabelled proteins far more quickly and easily – literally in a flash of light.

Drug Target Review – Issue 2 2019

5 June 2019 | By Drug Target Review

In this issue: novel approaches to produce radiolabelled antibodies, the use of CRISPR/Cas9 to accelerate the development of targeted therapies and utilisation of stem cells to study the effects of cannabis on neuronal development.

New study brings universal flu vaccine a step closer

4 June 2019 | By Drug Target Review

An international team of researchers has proven that targeting a specific area of the flu virus protects humans.