Antibodies

Monoclonal antibodies produced by new cell lines hope to improve drugs

1 August 2018 | By Drug Target Review

Many biopharmaceutical companies look to produce biosimilars soon, since the patents on the original mAb expire over the next few years...

IgM antibodies protect against HIV-1 infection

24 July 2018 | By Dr Zara Kassam (Drug Target Review)

A group of scientists have zeroed in on a new defence against HIV-1, the virus that causes AIDS...

Carterra

IgE protein may protect against skin cancer

18 July 2018 | By Dr Zara Kassam (Drug Target Review)

The components of the immune system that trigger allergic reactions may also help protect the skin against cancer, suggest new findings...

Tech note: Fast, simple, homogeneous assays for characterisation of Fc receptor binding using AlphaLISA

16 July 2018 | By Catherine Lautenschlager (PerkinElmer), Hong Cao (PerkinElmer)

AlphaLISA® provides a robust assay that facilitates the design and development of antibody therapeutics.

Brain cancer with mutation at EGFR alanine 289 may be susceptible to monoclonal antibody mAb806

11 July 2018 | By Iqra Farooq

Antibody mAb806 may be useful in treating aggressive forms of glioblastoma multiform...

Application note: Analyte quarterly Vol 1

29 June 2018 | By Merck KGaA

Your comprehensive guide to multiplex and single protein detection...

Mini-ecosystems developed to test a molecules therapeutic effect

20 June 2018 | By Drug Target Review

Research scientists have solved a major problem in chemistry and drug development by using droplet-sized 'mini-ecosystems to quickly see if a molecule can function as a potential therapeutic...

Targeting BAFF reduces the development of atherosclerosis

18 June 2018 | By Drug Target Review

The researchers identified that BAFF to have anti-inflammatory properties, which has a positive effect on plaque size and atherosclerosis...

Mouse IgG type and Titer Kit

15 June 2018 | By IntelliCyt

The Intellicyt Mouse IgG Type and Titer Kit is a high throughput, multiplexed assay kit that enables analyses of isotype, titer and cell health in a single assay...

Application note: A novel way to expedite antibody discovery

15 June 2018 | By IntelliCyt Corporation

Analyse isotype titer and cell health in one assay...

E06 antibody blocks inflammation from hardened arteries and liver disease

8 June 2018 | By Dr Zara Kassam (Drug Target Review)

Study uncovers new potential therapeutic approach for a number of diseases linked to inflammation, including atherosclerosis, aortic stenosis and hepatic steatosis...

Expert view: Biological therapeutics are becoming more popular, here are the reasons

7 June 2018 | By Dr. Paul Wylie (Head of Applications at TTP Labtech)

For most people, traditional High-Throughput Screening (HTS) represents large automation rigs and large libraries of small molecules screened against drug targets, however, the development of biological therapeutics has been gaining considerable pace for many reasons.

Expert view: Reviewing the biggest innovations in antibody screening

6 June 2018 | By Joseph Zock (Senior Director - Product Management - IntelliCyt -a Sartorius Company)

The demand for new therapeutics is driving efforts to discover novel antibodies and harness their power in both biologics and adoptive cell therapy areas.

Novel gene in red blood cells may help adult newts regenerate limbs

6 June 2018 | By Drug Target Review

Japan-US research collaboration has found that red blood cells that express a novel gene may contribute to adult newt limb regeneration.