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In this application note, PerkinElmer demonstrates the ease and utility of using LANCE® Ultra, a homogeneous assay format, for determining binding profiles of therapeutic monoclonal antibodies to FcγRs.
3 January 2018 | By PerkinElmer
Alpha (Amplified Luminescence Proximity Homogeneous Assay) bead-based technology for no-wash assays.
Massachusetts General Hospital (MGH) investigators use enzyme treatment to convert autoantibodies into anti-inflammatory antibodies in animal models of two autoimmune diseases.
DiscoverX recently introduced the single donor-derived KILR CD16 Effector Cells to ensure assay reproducibility for screening, characterisation, and QC lot release of antibody drugs.
In this application note, PerkinElmer demonstrate the utility of an AlphaLISA assay for screening biotherapeutic antibodies and compounds that block binding of human PD-1 and PD-L1.
Scientists at the University of Geneva (UNIGE) have deciphered the mechanisms that link obesity with type-2 diabetes at the cellular level, thus explaining the reasons behind an association that is already well known.
Antibody-based infrared fluorescent imaging can specifically distinguish cancer from normal tissue in patients with glioblastoma...
Blocking the action of two pro-inflammatory molecules can significantly reduce the symptoms of allergic asthma...
6 October 2017 | By DiscoverX Corporation
In this webinar, we discussed how two qualification studies on KILR CD16 Effector Cells demonstrated accuracy and precision in different assays formats.
Scientists have developed broad-spectrum inhibitors of the influenza virus using artificial peptide molecules...
In this whitepaper, IntelliCyt Corporation describe how the iQue Screener is used to perform multiplexed screens for antibody binding to either cell surface or to circulating target antigens...
27 September 2017 | By IntelliCyt Corporation
In this webinar, Belen Ybarrondo, Ph.D and Thomas Duensing, Ph.D discuss the challenges faced with antibody screening and how the iQue Screener can give an evaluation of cell killing mechanism, screening for immune checkpoint inhibitors and more...
Depletion of B cells in the tumour micro-environment shows anti-tumour activity in patients with advanced metastatic melanoma...
A three-pronged antibody has been found to protect from infection with two strains of SHIV, better than individual natural antibodies...
In this application note, PerkinElmer discuss how their ValiScreen CXCR2 GPCR cell line (#ES-145-C) was utilised to examine the downstream effects of chemokine receptor modulation using multiple blocking antibodies and a small molecule...
