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Application note: Afucosylated mAb expression & antibody efficacy
Sino Biological’s “FucoFree” eukaryotic expression system provides high-yield and high-throughput afucosylated monoclonal antibody (mAb) production.
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Antibodies
news
FDA accepts IND application for Clarametyx antibody therapy CMTX-101
Clarametyx says the FDA has accepted an IND application for first-in-human trials of CMTX-101, an antibody to treat bacterial pneumonia.
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Scientists push for development of intranasal COVID-19 vaccines
The best protection from COVID-19 will come from intranasally-delivered vaccines, due to the effectiveness of mucosal IgA antibodies, say researchers from the University at Buffalo.
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Is an HIV vaccine on the horizon?
Researchers in the US have developed a potential HIV vaccine approach that aims to prompt the creation of broadly neutralising antibodies via mRNA.
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Newly discovered SARS-CoV-2-like virus could infect humans and resist vaccines
A recently discovered SARS-CoV-2 virus in a Russian bat is likely to be capable of infecting humans and resistant to current vaccines.
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Application note: Fast-track antibody discovery: a high-throughput method for identifying and isolating rare secreting cells
Discover how picodroplet microfluidic technologies can identify and isolate 'hit' cells, quantify varying concentrations of antigen-specific antibodies and much more.
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In search of COVID-19 antibodies
Antibody therapy has been a critical part of the COVID-19 research campaign to treat severe cases. Unfortunately, despite many promising candidates, scientists have yet to find one that passes clinical trials. This article by Drug Target Review’s Ria Kakkad highlights some of the most recent developments in the search for COVID-19…
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New antibody shows promise in mice with Alzheimer’s disease
Scientists at UTHealth Houston have developed an agonistic antibody that reduced the amyloid pathology in mice with Alzheimer’s disease.
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T-cell redirecting bispecific antibodies: the next era of immune-based therapies for multiple myeloma?
While the introduction of novel immunotherapies to combat and treat cancer has advanced patient care greatly, ever more effective solutions continue to be required. Here, Dr Edmond Chan, Senior Director, EMEA Therapeutic Area Lead, Haemato-Oncology at Janssen Europe, Middle East & Africa (EMEA), explores how T-cell redirecting bispecific antibodies (TRBAs)…
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Monoclonal antibodies as a strategy to fight cancer
In this exclusive Q&A, Dr Veysel Kayser, Associate Professor at the University of Sydney, Australia, outlines why monoclonal antibodies (mAbs) are such an important tool to combat cancer. He also relates his recent research, as well as the latest trends in the industry.
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Drug Target Review Antibodies ebook 2022
In this ebook are articles on why monoclonal antibodies represent a high level of promise in the fight against cancer and how T-cell redirecting bispecific antibodies could work as a new immunotherapeutic strategy against haematological conditions.
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Drug Target Review – Issue 3 2022
In this issue are articles on synthetically engineered bacteria to deliver therapeutics, how single-molecule fluorescence resonance energy transfer was used to image GPCRs and a new assay to identify coronavirus drugs. Also included are pieces on vaccine development, monoclonal antibodies and neuroscience.
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Case Study: Trust in your results — A flow cytometry case study
Trust in your results — Experience the benefits of iQue® advanced flow cytometry.
podcasts
Episode 12 – ELISA assays with Dr Ana Miletic and Anna Dey, Kyowa Kirin & Dr Cathy Olsen, Molecular Devices
In this episode, experts discuss how they use ELISA assays in their research as well as the specific benefits of this kind of immunoassay.
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Whitepaper: Detecting CAR-T cells using Fluorokines™
This article outlines the advantages of using R&D Systems™ fluorescent-labeled proteins to directly stain and detect CAR+ cells by flow cytometry.