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Antibody Discovery

Rethinking antibody discovery in the age of automation

19 June 2025 | By Drug Target Review

James Atwood, COO of Opentrons, shares how accessible lab automation is helping research teams tackle tighter budgets, faster timelines and complex discovery workflows.

news

Dual-action therapy clears MDR bacteria in preclinical models

18 June 2025 | By Drug Target Review

Centauri Therapeutics has published data showing that CTX-09’s ability effectively clears drug-resistant Gram-negative bacteria through a novel dual mechanism, marking a promising development for new infection therapies.

article

Shifting the ADC focus from antibody to payload

6 June 2025 | By Drug Target Review

While ADCs continue to attract attention in oncology, many developers remain focused on antibodies – overlooking the critical role of payload design. At Sygnature Discovery, Dr Joshua Greally is leading a shift in perspective, advocating for a payload-first approach through the company’s new platform, NewPath ADC. In this interview, he…

webinar

Optimizing antibody leads in early drug discovery with key developability insights

5 June 2025 | By WuXi Biologics

Stop costly biologic failures. This masterclass reveals high-throughput strategies to optimize antibody leads upfront.

Science technology concept. A male scientist with the vaccine in the laboratory

article

Next-generation drug design: how generative AI can tackle undruggable targets

3 June 2025 | By Murat Tunaboylu (Co-founder of Antiverse)

Generative AI is broadening the boundaries of what is possible in drug discovery. In this article, Murat Tunaboylu, CEO and Co-founder of Antiverse, reveals how the zeitgeist technology is enabling scientists to tackle previously undruggable targets like GPCRs and ion channels to deliver patient impact faster.

article

Strategic planning in ADC development: insights from Lonza

2 June 2025 | By Drug Target Review

Preclinical and clinical development are critical to the success of ADCs, where early strategic decisions regarding manufacturability and scalability can make or break a project. Iwan Bertholjotti of Lonza emphasises the importance of proactive planning to avoid costly delays and ensure smooth progress towards clinical success.

Precision Oncology and Targeted Oncology Therapy - Area of medicine that Uses Personalized and Genomic-based Approaches to Diagnose and Treat Cancer

article

Next-gen ADCs: Tubulis sets new standard in cancer treatment

23 April 2025 | By Drug Target Review

Tubulis, led by CEO Dominik Schumacher, is advancing cancer treatment through next-generation antibody-drug conjugates (ADCs) designed to target solid tumours more effectively. Find out how the company is rapidly progressing its ADC pipeline to offer more precise and lasting treatment options for patients.

Antibodies, immunoglobulin Ig proteins 3D medical image. Immune system, IgM, IgG, IgE, IgD, IgA antibodies glycoproteins, specific antigens against virus. Vital components of the immunity response

news

FairJourney Biologics acquires Charles River’s South San Francisco facility

19 March 2025 | By Drug Target Review

FairJourney Biologics S.A., a global leader in antibody discovery and optimisation, has announced its acquisition of Charles River Laboratories’ South San Francisco site.

3D Rendering of Antibody Drug Conjugate - ADC

article

Refining and targeting exatecan with ADC technology

10 March 2025 | By Drug Target Review

DTR speaks with Dr Patrick van Berkel at ADC Therapeutics to discuss how the company is transforming exatecan delivery to achieve better health outcomes.

Multiple myeloma cells (MM) in blood flow

article

Cilta-cel: A new era in multiple myeloma treatment

29 January 2025 | By Carrie Haslam

New cell therapy, Cilta-cel, shows promise in the treatment of multiple myeloma, providing a personalised approach with the potential for long-term remission.

article

How GPCR agonists, including antibodies, are shaping the future of metabolic care

9 January 2025 | By Dr Cedric Ververken

Find out how Confo Therapeutics is overcoming challenges in GPCR drug development to create next-gen therapies for metabolic diseases.

article

New research improves the safety and effectiveness of ADC cancer treatments

26 December 2024 | By Drug Target Review

Learn how the University at Buffalo is pioneering safer, more effective ADC therapies.

article

New targeted therapies show promise in lung cancer treatment

13 December 2024 | By Dr Eleni Lagkadinou (Vice President of Oncology Early Development at AbbVie)

Recent advancements in targeted therapies and immunotherapies are transforming lung cancer treatment. Discover how these innovations are improving outcomes and providing hope for patients.

news

New platform will accelerate single-cell analysis workflow

3 October 2024 | By Drug Target Review

Sphere Fluidics have developed the Cyto-Mine® Chroma platform, which provides multiplexing and greater assay flexibility, reducing timelines and cost.

news

Epstein-Barr virus: new targets for vaccine design and treatment

13 March 2024 | By Drug Target Review

A lab generated monoclonal antibody prevented EBV infection and EBV lymphomas in rodent models and could have future clinical applications.

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Antibody Discovery